https://scholars.lib.ntu.edu.tw/handle/123456789/517919
標題: | Development and validation of a dementia screening tool for primary care in Taiwan: Brain Health Test | 作者: | Tsai P.-H. Liu J.-L. Lin K.-N. Chang C.-C. Pai M.-C. Wang W.-F. Huang J.-P. TZUNG-JENG HWANG Wang P.-N. |
公開日期: | 2018 | 卷: | 13 | 期: | 4 | 起(迄)頁: | e0196214 | 來源出版物: | PLoS ONE | 摘要: | Objectives To develop a simple dementia screening tool to assist primary care physicians in identifying patients with cognitive impairment among subjects with memory complaints or at a high risk for dementia. Design The Brain Health Test (BHT) was developed by several experienced neurologists, psychiatrists, and clinical psychologists in the Taiwan Dementia Society. Validation of the BHT was conducted in the memory clinics of various levels of hospitals in Taiwan. Participants All dementia patients at the memory clinics who met the inclusion criteria of age greater or equal to 50 years were enrolled. Besides the BHT, the Mini-Mental State Examination and Clinical Dementia Rating were used to evaluate the cognition state of the patients and the severity of dementia. Results The BHT includes two parts: a risk evaluation and a cognitive test (BHT-cog). Self or informants reports of memory decline or needing help from others to manage money or medications were significantly associated with cognitive impairment. Among the risk factors evaluated in the BHT, a total risk score greater or equal to 8 was defined as a high risk for dementia. The total score for the finalized BHT-cog was 16. When the cutoff value for the BHT-cog was set to 10 for differentiating dementia and a normal mental state, the sensitivity was 91.5%, the specificity was 87.3%, the positive predictive value was 94.8%, and the negative predictive value was 80.1% The area under the receiver operating characteristic curve between dementia and healthy subjects was 0.958 (95% CI = 0.941–0.975). Conclusions The BHT is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening. ? 2018 Tsai et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045890234&doi=10.1371%2fjournal.pone.0196214&partnerID=40&md5=b8315a3162f1758aed5b090b52441acf https://scholars.lib.ntu.edu.tw/handle/123456789/517919 |
ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0196214 | SDG/關鍵字: | adult; age; aged; Article; Brain Health Test; clinical assessment tool; Clinical Dementia Rating; cognitive defect; controlled study; dementia; diagnostic test accuracy study; diagnostic value; disease severity; female; high risk patient; human; major clinical study; male; memory disorder; mental task; middle aged; Mini Mental State Examination; neurologist; physician; predictive value; primary medical care; psychiatrist; psychologist; receiver operating characteristic; risk assessment; risk factor; screening test; self report; sensitivity and specificity; Taiwan; validation study; clinical trial; cognition assessment; cognitive defect; dementia; dementia assessment; differential diagnosis; early diagnosis; multicenter study; neuropsychological test; primary health care; psychology; very elderly; Aged; Aged, 80 and over; Cognitive Dysfunction; Dementia; Diagnosis, Differential; Early Diagnosis; Female; Humans; Male; Memory and Learning Tests; Mental Status and Dementia Tests; Neuropsychological Tests; Primary Health Care; ROC Curve; Taiwan |
顯示於: | 醫療器材與醫學影像研究所 |
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