https://scholars.lib.ntu.edu.tw/handle/123456789/518209
標題: | Trismus, xerostomia and nutrition status in nasopharyngeal carcinoma survivors treated with radiation | 作者: | Chen Y.-J. Chen S.-C. CHENG-PING WANG Fang Y.-Y. YUN-HSIANG LEE PEI-JEN LOU JENG-YUH KO Chiang C.-C. YEUR-HUR LAI |
公開日期: | 2016 | 出版社: | Blackwell Publishing Ltd | 卷: | 25 | 期: | 3 | 起(迄)頁: | 440-448 | 來源出版物: | European Journal of Cancer Care | 摘要: | The aims of the study were to: (1) examine levels of trismus, xerostomia and nutritional status; (2) compare levels of trismus, xerostomia and nutritional status in patients with nasopharyngeal carcinoma (NPC) receiving different types of radiation modalities; and (3) identify factors related to NPC survivors' risk status for malnutrition and existing malnutrition. A cross-sectional study with consecutive sampling was conducted. NPC survivors were recruited from otolaryngology/oncology outpatient clinics in a medical centre in Northern Taiwan. Study measures included (1) Mandibular Function Impairment Questionnaire, (2) Xerostomia Questionnaire, (3) Mini Nutrition Assessment, (4) Hospital Anxiety and Depression Scale - Depression subscale, and (5) Symptom Severity Scale. A total of 110 subjects were recruited. Those receiving intensity-modulated radiation therapy had less trismus and xerostomia than patients receiving two-dimensional radiation therapy. Patients with female gender, advanced stage, completion of treatments within 1 year, higher levels of depression, more severe trismus and higher symptom severity tended to have malnutrition or were at risk of malnutrition. Trismus and xerostomia are long-term problems in some NPC survivors and may contribute to malnutrition. To better manage a patient's trismus and xerostomia and to enhance nutritional status, clinicians should develop a patient-specific care programme based on careful assessment and targeted measures to improve oral function and insure adequate nutritional intake. © 2016 John Wiley & Sons Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920719145&doi=10.1111%2fecc.12270&partnerID=40&md5=41bbeb62b19d2d47401fdd9ab8b17dba https://scholars.lib.ntu.edu.tw/handle/123456789/518209 |
ISSN: | 0961-5423 | DOI: | 10.1111/ecc.12270 | SDG/關鍵字: | adverse effects; cross-sectional study; Depressive Disorder; female; health status indicator; human; intensity modulated radiation therapy; male; malnutrition; middle aged; Nasopharyngeal Neoplasms; nutritional status; radiation response; trismus; xerostomia; Cross-Sectional Studies; Depressive Disorder; Female; Health Status Indicators; Humans; Male; Malnutrition; Middle Aged; Nasopharyngeal Neoplasms; Nutritional Status; Radiotherapy; Radiotherapy, Intensity-Modulated; Trismus; Xerostomia |
顯示於: | 醫學系 |
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