https://scholars.lib.ntu.edu.tw/handle/123456789/518282
標題: | Rare involvement of submandibular gland by oral squamous cell carcinoma | 作者: | TSENG-CHENG CHEN Lo W.-C JENG-YUH KO PEI-JEN LOU TSUNG-LIN YANG CHENG-PING WANG |
公開日期: | 2009 | 卷: | 31 | 期: | 7 | 起(迄)頁: | 877-881 | 來源出版物: | Head and Neck | 摘要: | Background. The true involvement of the submandibular gland in primary oral cancer seems quite uncommon. Methods. We retrospectively reviewed the pathologic records of 342 patients with oral squamous cell carcinoma who underwent wide excision of primary oral cancer and simultaneous neck dissection from January 2000 to December 2003. Results. Of the 383 submandibular glands, only 7 (1.8%) exhibited tumor involvement. Of them, 5 glands were involved by direct extension from the primary tumor. One gland showed local invasion from an adjacent involved lymph node in level I and 1 was from intraglandular lymph node metastasis. All of these 6 tumors with submandibular gland involvement were T4 disease (p = .0003) and the neck nodal status on each was more than N2b (p < .0001). Conclusion. The patients with early-stage oral squamous cell carcinoma with preoperative N0 neck may be candidates for preservation of the submandibular gland. ? 2009 Wiley Periodicals, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-67650490317&doi=10.1002%2fhed.21039&partnerID=40&md5=ed9e8c440260d76039f6bb0a664a06a8 https://scholars.lib.ntu.edu.tw/handle/123456789/518282 |
ISSN: | 1043-3074 | DOI: | 10.1002/hed.21039 | SDG/關鍵字: | adult; aged; article; cancer incidence; cancer invasion; cancer risk; cancer surgery; disease severity; female; human; lymph node metastasis; major clinical study; male; mouth carcinoma; neck dissection; predictor variable; preoperative evaluation; primary tumor; priority journal; retrospective study; squamous cell carcinoma; submandibular gland; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Retrospective Studies; Risk Factors; Submandibular Gland; Young Adult |
顯示於: | 醫學系 |
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