https://scholars.lib.ntu.edu.tw/handle/123456789/519518
標題: | Behavioral and psychologic symptoms in different types of dementia | 作者: | MING-JANG CHIU TA-FU CHEN Yip P.-K. Hua M.-S. Tang L.-Y. |
公開日期: | 2006 | 出版社: | Scientific Communications International Ltd | 卷: | 105 | 期: | 7 | 起(迄)頁: | 556-562 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/Purpose: Behavioral and psychologic symptoms of dementia (BPSD) are major sources of a caregiver's burden and also the most important factor when considering the need for institutionalization of dementia patients. BPSD occur in about 90% of patients with dementia. Studies comparing the BPSD in the major types of dementia using unitary behavioral rating scales are limited. We studied BPSD in patients with four major types of dementias from a memory clinic. Methods: We recruited patients with dementia from our memory clinic from January 2003 to February 2004. The Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD) was used to measure BPSD severity. Clinical Dementia Rating and Mini Mental State Examination were used to determine dementia severity. Results: A total of 137 patients with four major types of dementia were recruited from 155 patients with dementia who attended the clinic during the study period. The main dementia types identified were Alzheimer's dementia (AD) in 54.8%, vascular dementia (VaD) in 20.6%, frontotemporal dementia (FTD) in 8.4%, dementia with Lewy bodies (DLB) in 4.5%, and other dementias in 11.6%. BPSD were found in 92.0% of the patients but only 43.1% received psychotropic treatment. The relative risk of receiving psychotropic treatment for BPSD subscales paralleled the extent of caregivers' burden as assessed by the BEHAVE-AD global rating. Type-specific BPSD, e.g. hallucination was identified for DLB, activity disturbances for FTD, anxiety and phobias for AD and affective disturbance for VaD. Conclusion: A strategy of targeting type-specific BPSD may be beneficial, such as environmental stimulus control for DLB patients who are prone to have hallucinations, design of a pacing path for patients with FTD who need support for symptoms of wandering and emotional support for patients with VaD who are susceptible to depression. ? 2006 Elsevier & Formosan Medical Association. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746974380&doi=10.1016%2fS0929-6646%2809%2960150-9&partnerID=40&md5=52219754c27885fef9e64e2eb856e926 https://scholars.lib.ntu.edu.tw/handle/123456789/519518 |
ISSN: | 0929-6646 | DOI: | 10.1016/S0929-6646(09)60150-9 | SDG/關鍵字: | psychotropic agent; Alzheimer disease; anxiety disorder; article; behavior disorder; caregiver burden; controlled study; dementia; diffuse Lewy body disease; disease severity; frontotemporal dementia; hallucination; human; major clinical study; mental disease; mini mental state examination; mood disorder; multiinfarct dementia; outpatient department; phobia; rating scale; risk assessment; risk factor; symptomatology; treatment planning |
顯示於: | 醫學系 |
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