https://scholars.lib.ntu.edu.tw/handle/123456789/521366
標題: | Surgical treatment of gastric gastrointestinal stromal tumors: Analysis of 92 operated patients | 作者: | I-RUE LAI CHIUNG-NIEN CHEN MING-TSAN LIN PO-HUANG LEE |
公開日期: | 2008 | 卷: | 25 | 期: | 3 | 起(迄)頁: | 208-212 | 來源出版物: | Digestive Surgery | 摘要: | Aim: To review and evaluate the clinicopathological factors predictive of recurrence after surgical resection for gastrointestinal stromal tumor (GIST) of the stomach. Methods: The clinicopathological records of 92 gastric GIST patients who were operated upon at a single institute from 1996 to 2005 were retrospectively reviewed and assessed for recurrence-free survival. Results: The patients included 43 men and 49 women. Their ages ranged from 25 to 91 years. The size of the tumors varied from 0.8 to 47.7 cm (median 5.8; 95% CI 6.4-9.2 cm). All but one operative margin were clear. The follow-up period ranged from 11 to 112 months (median 31, 95% CI 33.7-43.5 months). Fifteen patients (16%) developed disease recurrence, of which liver metastasis was the most common. Only 1 of the patients with tumors <4 cm developed recurrence. The 3-year recurrence-free survival rates for patients with tumors smaller or larger than 4 cm were 93 and 56.0%, respectively (p < 0.01). Multivariate analysis showed that the tumor size was the independent factor that was inversely associated with recurrence-free survival. Conclusion: The tumor size is an important prognostic factor for recurrence after surgery. Early excision is recommended for gastric GISTs even of small size. Copyright ? 2008 S. Karger AG. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-49449118028&doi=10.1159%2f000140691&partnerID=40&md5=191eaaa478b53a5eab9ed62ceeae779f https://scholars.lib.ntu.edu.tw/handle/123456789/521366 |
ISSN: | 0253-4886 | DOI: | 10.1159/000140691 | SDG/關鍵字: | adult; aged; article; cancer patient; cancer recurrence; cancer survival; female; follow up; gastrointestinal stromal tumor; human; independent variable; liver metastasis; major clinical study; male; retrospective study; survival rate; survival time; tumor volume; Adult; Aged; Aged, 80 and over; Disease-Free Survival; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; Humans; Liver Neoplasms; Male; Mesenchymoma; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Retrospective Studies; Risk Assessment; Stomach Neoplasms |
顯示於: | 醫學系 |
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