https://scholars.lib.ntu.edu.tw/handle/123456789/521639
Title: | Clinicopathologic characteristics of helicobacter pyloric seropositive gastric adenocarcinomas | Authors: | Lee W.-J. Lin J.-T. WEN-CHUNG LEE CHIA-TUNG SHUN RUEY-LONG HONG ANN-LII CHENG PO-HUANG LEE Wei T.-C. Chen K.-M. |
Issue Date: | 1995 | Journal Volume: | 21 | Journal Issue: | 3 | Start page/Pages: | 203-207 | Source: | Journal of Clinical Gastroenterology | Abstract: | To compare and characterize retrospectively the clinicopathologic features of gastric cancers with and without previous Helicobacter pylori infection, we determined the preoperative seropositivity of H. pylori in 151 patients who had undergone gastric resection for primary gastric adenocarcinoma between 1988 and 1993. The overall seroprevalence of H. pylori was 60.9%. H. pylori-positive gastric cancers were frequently associated (p < 0.05) with macroscopic localized types (Borrmann I and II) in which negative cancer associated with infiltrative types (Borrmann III and IV) and cancer invasion of the duodenum. Multivariate analysis showed that H. pylori seropositivity was not an independent prognostic factor. Pathologic tumor–node–metastases (TNM) stage remained the only prognostic indicator. Our study suggests that H. pylori has a significant impact on the clinically relevant tumor biology of gastric cancer. Investigation along this line is warranted. ? 1995 Lippincott-Raven Publishers, Philadelphia. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028981198&doi=10.1097%2f00004836-199510000-00007&partnerID=40&md5=78e5e994a5a149f62089f707e02dcc44 https://scholars.lib.ntu.edu.tw/handle/123456789/521639 |
ISSN: | 0192-0790 | DOI: | 10.1097/00004836-199510000-00007 | SDG/Keyword: | adult; aged; article; bacterium detection; cancer staging; diagnostic value; female; helicobacter pylori; human; major clinical study; male; priority journal; prognosis; stomach adenocarcinoma; Adenocarcinoma; Aged; Antibodies, Viral; Female; Helicobacter Infections; Helicobacter pylori; Human; Male; Middle Age; Prognosis; Retrospective Studies; Stomach Neoplasms; Support, Non-U.S. Gov't; Survival Rate |
Appears in Collections: | 醫學系 |
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