https://scholars.lib.ntu.edu.tw/handle/123456789/522060
Title: | Relationship between pancreatic cancer-associated diabetes and cachexia | Authors: | WEI-CHIH LIAO Chen, Peng-Ruei Huang, Cheng-Chieh Chang, Yen-Tzu Huang, Bo-Shih CHIN-CHEN CHANG MING-SHIANG WU LU-PING CHOW |
Keywords: | Cachexia; Diabetes; Pancreatic cancer; Sarcopenia | Issue Date: | Aug-2020 | Publisher: | WILEY | Journal Volume: | 11 | Journal Issue: | 4 | Start page/Pages: | 899 | Source: | Journal of cachexia, sarcopenia and muscle | Abstract: | Pancreatic cancer-associated diabetes mellitus (PCDM) is a paraneoplastic phenomenon characterized by worsening hyperglycaemia and weight loss. Galectin-3 and S100A9, mediators of PCDM, have pro-inflammatory functions and might thereby induce systemic inflammation and cachexia. We aimed to examine whether PCDM directly mediates cachexia. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/522060 | ISSN: | 2190-5991 | DOI: | 10.1002/jcsm.12553 | SDG/Keyword: | calgranulin B; galectin 3; glucose; hemoglobin A1c; adult; Article; body mass; body weight loss; cachexia; cancer size; cancer staging; clinical feature; diabetes mellitus; diabetic patient; disease association; fasting; female; glucose blood level; human; hyperglycemia; logistic regression analysis; major clinical study; male; middle aged; muscle mass; pancreas cancer; paraspinal muscle; primary tumor; priority journal; protein blood level; sarcopenia; skeletal muscle; cachexia; complication; diabetes mellitus; pancreas tumor; pathophysiology; Cachexia; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms |
Appears in Collections: | 生物化學暨分子生物學科研究所 |
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