https://scholars.lib.ntu.edu.tw/handle/123456789/522460
Title: | Acute bilateral diffuse corneal opacity in a child | Authors: | Wang T.-J. Hsiao C.-H. FUNG-RONG HU I-JONG WANG YU-CHIH HOU |
Issue Date: | 2007 | Journal Volume: | 26 | Journal Issue: | 3 | Start page/Pages: | 375-378 | Source: | Cornea | Abstract: | PURPOSE: To report a case of acute bilateral corneal opacity related to bacterial blepharoconjunctivitis. METHODS: Interventional case report. An 18-month-old boy had bilateral red eyes with discharge and periorbital eczema. Bilateral corneal opacity suddenly developed 1 week later. RESULTS: All clinical assessments and laboratory evaluations of viral infection and autoimmune profiles were negative except for growth of coagulase-negative staphylococcus and propionibacterium acnes from conjunctival discharge. After systemic and topical antibiotic treatment, the opacity and inflammation of both eyes decreased. The left cornea became clear, but the right eye had a sequela of corneal opacity with stromal neovascularization and conjunctival scarring. Penetrating keratoplasty was performed in the right eye 6 months later. Histology at that time showed neovascularization in the deep stroma with perivascular mononuclear cell infiltration and decreased endothelial cells. CONCLUSIONS: Acute bilateral corneal opacity is rare but may occur in children with bacterial blepharokeratoconjunctivitis. Ocular surface inflammation may be induced by bacterial toxin reaction. Combined use of antibiotics and steroids may save the vision in such patients. ? 2007 Lippincott Williams & Wilkins, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34147143870&doi=10.1097%2fICO.0b013e31802eaf7a&partnerID=40&md5=b356147a5fa425c7eb103199ac124db2 https://scholars.lib.ntu.edu.tw/handle/123456789/522460 |
ISSN: | 0277-3740 | DOI: | 10.1097/ICO.0b013e31802eaf7a | SDG/Keyword: | aciclovir; ampicillin; ciprofloxacin; sulbactam; sultamicillin; article; case report; cell infiltration; clinical feature; conjunctiva; cornea; cornea edema; cornea opacity; endothelium cell; evaluation; eye inflammation; histology; human; laboratory test; male; mononuclear cell; neovascularization (pathology); penetrating keratoplasty; preschool child; priority journal; Propionibacterium; Staphylococcus; Acute Disease; Ampicillin; Anti-Bacterial Agents; Blepharitis; Conjunctivitis; Corneal Edema; Corneal Opacity; Drug Therapy, Combination; Eye Infections, Bacterial; Gram-Positive Bacterial Infections; Humans; Infant; Male; Propionibacterium acnes; Sulbactam [SDGs]SDG3 |
Appears in Collections: | 醫學系 |
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