https://scholars.lib.ntu.edu.tw/handle/123456789/523010
標題: | Vitamin D insufficiency and frailty syndrome in older adults living in a Northern Taiwan community. | 作者: | Chang C.I. DING-CHENG CHAN Kuo K.N. Hsiung C.A. CHING-YU CHEN |
關鍵字: | Edmonton Frail Scale; Elderly in Taiwan; Fried Frailty Index; Vitamin D insufficiency | 公開日期: | 2010 | 卷: | 50 Suppl 1 | 起(迄)頁: | S17-21 | 來源出版物: | Archives of gerontology and geriatrics | 摘要: | This study explored the association between vitamin D insufficiency and frailty syndrome defined by the Fried Frailty Index (FFI) and the Edmonton Frail Scale (EFS) in a northern Taiwan community. Data of 215 subjects participating in an integrated interventional trial involving community-dwelling older adults with a high frailty risk were analyzed. Subjects were first screened by telephone interview and then evaluated at a local hospital with questionnaires, physical performance tests, and serum 25(OH)D measurements. Of the 215 participants, 31% had 25(OH)D insufficiency (< 20 ng/ml). Frail subjects based on the FFI were older, had lower Mini-Mental Status Exam (MMSE) scores, Barthel Index (BI) scores, and 25(OH)D levels. Using the EFS, frailer cases were more likely to be female, have less education, higher comorbid conditions, lower MMSE scores, lower Barthel Index scores, and lower 25(OH)D levels. The associations between insufficient 25(OH)D status and both frailty scales were significant. After adjustment of variables, the odds ratio of 25(OH)D insufficiency was 10.74 (95% CI 2.60–44.31) for frail versus robust individuals. The prevalence of vitamin D insufficiency was high in this population. There was a strong association between vitamin D insufficiency and the FFI. Vitamin D measurements and supplements are suggested for high-risk older people. ? 2010 Elsevier Ltd |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77952538830&partnerID=40&md5=853444c564ea15c176625f7772c436ed https://scholars.lib.ntu.edu.tw/handle/123456789/523010 |
ISSN: | 1872-6976 | SDG/關鍵字: | aged; article; cognitive defect; female; frail elderly; hospitalization; human; male; neuropsychological test; residential care; risk factor; statistics; Taiwan; vitamin D deficiency; Aged; Catchment Area (Health); Cognition Disorders; Female; Frail Elderly; Humans; Male; Neuropsychological Tests; Risk Factors; Severity of Illness Index; Taiwan; Vitamin D Deficiency |
顯示於: | 醫學系 |
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