https://scholars.lib.ntu.edu.tw/handle/123456789/523868
標題: | Timing of tracheostomy as a determinant of weaning success in critically ill patients: a retrospective study. | 作者: | CHIA-LIN HSU KUAN-YU CHEN CHIA-HSUIN CHANG JIH-SHUIN JERNG CHONG-JEN YU PAN-CHYR YANG |
公開日期: | 2005 | 卷: | 9 | 期: | 1 | 起(迄)頁: | R46-52 | 來源出版物: | Critical care (London, England) | 摘要: | INTRODUCTION: Tracheostomy is frequently performed in critically ill patients for prolonged intubation. However, the optimal timing of tracheostomy, and its impact on weaning from mechanical ventilation and outcomes in critically ill patients who require mechanical ventilation remain controversial. METHODS: The medical records of patients who underwent tracheostomy in the medical intensive care unit (ICU) of a tertiary medical centre from July 1998 to June 2001 were reviewed. Clinical characteristics, length of stay in the ICU, rates of post-tracheostomy pneumonia, weaning from mechanical ventilation and mortality rates were analyzed. RESULTS: A total of 163 patients (93 men and 70 women) were included; their mean age was 70 years. Patients were classified into two groups: successful weaning (n = 78) and failure to wean (n = 85). Shorter intubation periods (P = 0.02), length of ICU stay (P = 0.001) and post-tracheostomy ICU stay (P = 0.005) were noted in patients in the successful weaning group. Patients who underwent tracheostomy more than 3 weeks after intubation had higher ICU mortality rates and rates of weaning failure. The length of intubation correlated with the length of ICU stay in the successful weaning group (r = 0.70; P < 0.001). Multivariate analysis revealed that tracheostomy after 3 weeks of intubation, poor oxygenation before tracheostomy (arterial oxygen tension/fractional inspired oxygen ratio <250) and occurrence of nosocomial pneumonia after tracheostomy were independent predictors of weaning failure. CONCLUSION: The study suggests that tracheostomy after 21 days of intubation is associated with a higher rate of failure to wean from mechanical ventilation, longer ICU stay and higher ICU mortality. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-23744460037&partnerID=40&md5=3991f52bfdc738c0490f72cf6334a489 https://scholars.lib.ntu.edu.tw/handle/123456789/523868 |
ISSN: | 1466-609X | SDG/關鍵字: | aged; APACHE; article; artificial ventilation; critical illness; female; human; intensive care unit; length of stay; male; methodology; mortality; retrospective study; time; tracheostomy; Aged; APACHE; Critical Illness; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Respiration, Artificial; Retrospective Studies; Time Factors; Tracheostomy; Ventilator Weaning |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。