https://scholars.lib.ntu.edu.tw/handle/123456789/523899
標題: | Clinical Manifestations, Laboratory Findings, and Treatment Outcomes of SARS Patients | 作者: | JANN-TAY WANG WANG-HUEI SHENG CHI-TAI FANG YEE-CHUN CHEN Wang J.-L. CHONG-JEN YU SHAN-CHWEN CHANG PAN-CHYR YANG |
公開日期: | 2004 | 出版社: | Centers for Disease Control and Prevention (CDC) | 卷: | 10 | 期: | 5 | 起(迄)頁: | 818-824 | 來源出版物: | Emerging Infectious Diseases | 摘要: | Clinical and laboratory data on severe acute respiratory syndrome (SARS), particularly on the temporal progression of abnormal laboratory findings, are limited. We conducted a prospective study on the clinical, radiologic, and hematologic findings of SARS patients with pneumonia, who were admitted to National Taiwan University Hospital from March 8 to June 15, 2003. Fever was the most frequent initial symptom, followed by cough, myalgia, dyspnea, and diarrhea. Twenty-four patients had various underlying diseases. Most patients had elevated C-reactive protein (CRP) levels and lymphopenia. Other common abnormal laboratory findings included leukopenia, thrombocytopenia, and elevated levels of aminotransferase, lactate dehydrogenase, and creatine kinase. These clinical and laboratory findings were exacerbated in most patients during the second week of disease. The overall case-fatality rate was 19.7%. By multivariate analysis, underlying disease and initial CRP level were predictive of death. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-2142809650&doi=10.3201%2feid1005.030640&partnerID=40&md5=d2d5f53e67e964459d34767dd6b26b41 https://scholars.lib.ntu.edu.tw/handle/123456789/523899 |
ISSN: | 1080-6040 | DOI: | 10.3201/eid1005.030640 | SDG/關鍵字: | aminotransferase; C reactive protein; creatine kinase; immunoglobulin; lactate dehydrogenase; methylprednisolone; ribavirin; steroid; adult; aged; article; clinical feature; coughing; death; diarrhea; disease exacerbation; dyspnea; fatality; female; fever; human; laboratory test; lymphocytopenia; major clinical study; male; myalgia; pneumonia; prospective study; severe acute respiratory syndrome; symptomatology; thrombocytopenia; treatment outcome |
顯示於: | 醫學系 |
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