Ultrasound guided pericardial drainage and intrapericardial instillation of mitomycin C for malignant pericardial effusion
Journal
Thorax
Journal Volume
49
Journal Issue
6
Pages
594-595
Date Issued
1994
Author(s)
Abstract
Background - Conservative treatment of malignant pericardial effusion by intrapericardial instillation of a sclerosing agent may be an alternative to surgery. Methods - Twenty patients with malignant pericardial effusion were treated by ultrasound guided pericardiocentesis and the intrapericardial instillation of mitomycin C. Results - Mitomycin C was effective in controlling the pericardial effusion in 70% of patients without causing side effects, except for pericardial constriction seven months later in one subject. Conclusions - Ultrasound guided intrapericardial instillation of mitomycin C is a suitable alternative in the management of malignant pericardial effusion.
SDGs
Other Subjects
mitomycin c; sclerosing agent; adult; aged; article; cancer; clinical article; clinical trial; drug efficacy; female; human; male; pericardial effusion; pericardiocentesis; priority journal; survival rate; ultrasound; Adult; Aged; Combined Modality Therapy; Drainage; Female; Human; Injections, Intralesional; Lung Neoplasms; Male; Middle Age; Mitomycin; Pericardial Effusion
Publisher
BMJ Publishing Group
Type
journal article