Relationship of adiposity and body composition to the status of metabolic syndrome among ethnic Chinese Taiwanese
Journal
Nutrition, Metabolism and Cardiovascular Diseases
Journal Volume
21
Journal Issue
9
Pages
643-650
Date Issued
2011
Author(s)
Abstract
Background and aims: The predictive power of adiposity and body compositions measured from bioelectrical impedance analysis (BIA) for identifying the risk of metabolic syndrome is unknown among ethnic Chinese. Methods and results: We designed a nested case-control study by recruiting 1000 cases of metabolic syndrome and 986 matched controls from a health checkup center. For identifying the metabolic syndrome status, the highest areas under receiver operating characteristic curve (AUCs) were waist-height ratio (WHtR) (0.967, 95% confidence interval [CI], 0.960-0.976). The body fat mass vs. lean body mass and body mass index (BMI) had a similar AUC (0.896 for fat mass vs. lean body mass, 0886 for BMI, P= 0.07). WHtR and waist circumference had the highest correctly classified proportions (0.89-0.90) and the highest Youden's index (0.77-0.81). The optimal cut point for WHtR was 52.5, with a sensitivity of 0.92 and specificity of 0.89 for discriminating metabolic syndrome risk. The incremental values of AUC, net reclassification improvement and integrated discrimination improvement values were still highest among WHtR, waist circumference and the percent body fat in the multivariate logistic model. Conclusion: Waist circumference and BIA-derived body component measures are suitable for clinical application in identifying the metabolic syndrome status among ethnic Chinese in Taiwan. ? 2010.
Other Subjects
adipose tissue; adult; aged; article; body height; body mass; case control study; China; ethnology; female; human; impedance; male; metabolic syndrome X; middle aged; multivariate analysis; obesity; receiver operating characteristic; statistical model; Taiwan; waist circumference; Adipose Tissue; Adiposity; Adult; Aged; Body Height; Body Mass Index; Case-Control Studies; China; Electric Impedance; Female; Humans; Logistic Models; Male; Metabolic Syndrome X; Middle Aged; Multivariate Analysis; ROC Curve; Taiwan; Waist Circumference
Type
journal article