https://scholars.lib.ntu.edu.tw/handle/123456789/524392
標題: | Drug-related problems vary with medication category and treatment duration in Taiwanese heart failure outpatients receiving case management | 作者: | WAN-TSENG HSU LI-JIUAN SHEN CHII-MING LEE |
公開日期: | 2016 | 出版社: | Elsevier B.V. | 卷: | 115 | 期: | 5 | 起(迄)頁: | 335-342 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/purpose: Heart failure (HF) patients are at high risk of having drug-related problems (DRPs). We aim to describe the frequency, types, and temporal occurrence of DRPs in Taiwanese HF outpatients receiving case management. Methods: In this study, we included 141 patients from HF clinics in three hospitals in Taiwan from October 2008 to December 2010. Nurse case managers at each of the participating sites registered case report forms (CRFs) for patients during clinic visits. DRPs were classified using the Pharmaceutical Care Network Europe Foundation (PCNE) classification system and documented by pharmacists after reviewing CRFs and participating in multidisciplinary team discussions. Results: For 141 clinic participants, the average duration of medication use was 17 months, and 796 DRPs were reported. The DRPs most frequently recorded were the need for laboratory tests (32.7% of total DRPs), followed by potential interaction (29.6%), nonallergic side effects (13.3%), and insufficient awareness of health and disease (9.5%). The drugs most frequently causing a DRP were angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, diuretics, warfarin, spironolactone, and β-blockers. The incidence rates of total DRPs was maximal during the initial 3 months of medication treatment, whereas the incidence rates of each category of DRPs showed multiform changes over time among various drug classes. Conclusion: In Taiwan where the clinical pharmacist system is not well organized, HF outpatients still had a high prevalence of DRPs despite intensive monitoring by nurse case managers. Clinical pharmacists play critical roles in detecting potential DRPs during long-term medication treatment for this population. ? 2015. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84965066386&doi=10.1016%2fj.jfma.2015.11.014&partnerID=40&md5=6f7e5e669bbaf68cdd444a49bf3af142 https://scholars.lib.ntu.edu.tw/handle/123456789/524392 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2015.11.014 | SDG/關鍵字: | amiodarone; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; digoxin; dipeptidyl carboxypeptidase inhibitor; diuretic agent; hydroxymethylglutaryl coenzyme A reductase inhibitor; spironolactone; warfarin; beta adrenergic receptor blocking agent; dipeptidyl carboxypeptidase inhibitor; diuretic agent; spironolactone; warfarin; adult; Article; awareness; cardiologist; case management; case manager; drug abuse; drug related problem; female; follow up; heart failure; human; incidence; laboratory test; major clinical study; male; medical documentation; outpatient; pharmaceutical care; pharmacist; retrospective study; Taiwan; Taiwanese; treatment duration; aged; ambulatory care; case management; clinical trial; drug interaction; Drug-Related Side Effects and Adverse Reactions; heart failure; middle aged; multicenter study; outpatient; prospective study; Adrenergic beta-Antagonists; Aged; Ambulatory Care; Angiotensin-Converting Enzyme Inhibitors; Case Management; Diuretics; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Heart Failure; Humans; Male; Middle Aged; Outpatients; Prospective Studies; Spironolactone; Taiwan; Warfarin |
顯示於: | 醫學系 |
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