https://scholars.lib.ntu.edu.tw/handle/123456789/524976
標題: | Effects of influenza vaccine and sun exposure time against laboratory-confirmed influenza hospitalizations among young children during the 2012–13 to 2015–16 influenza seasons | 作者: | Wang C.-Y. Chang Y.-H. LI-MIN HUANG Chi H. Chiu N.-C. LUAN-YIN CHANG CHUN-YI LU Huang Y.-C. Lin H.-C. JIAN-TE LEE Liu C.-C. Huang Y.-C. Ho Y.-H. Tu Y.-H. Wang J.-Y. Huang D.T.-N. Taiwan Pediatric Infectious Disease Alliance |
公開日期: | 2019 | 出版社: | Elsevier Ltd | 卷: | 52 | 期: | 6 | 起(迄)頁: | 880-887 | 來源出版物: | Journal of Microbiology, Immunology and Infection | 摘要: | Background: Influenza is a major cause of acute respiratory infection burden worldwide, leading to many hospitalizations. An annual influenza vaccine is believed to be the best way to prevent influenza-related illnesses. We focused on the efficacies of other possible preventive measures such as increasing sun exposure time and dietary supplements to prevent these illnesses. Methods: We conducted a matched-pair case–control study along with the Taiwan Pediatric Infectious Disease Alliance. We included influenza-related hospitalized patients with age ranging from 6 months to 5 years during the 2012–2013, 2013–2014, 2014–2015, and 2015–2016 influenza seasons. The controls were comparable to cases in age, sex, and residential area and had no influenza-related hospitalization records in the same season. We extracted data from vaccination histories and got the patients’ guardians to complete questionnaires. Data were analyzed using conditional logistic regression. Results: We enrolled 1514 children (421 influenza-infected cases and 1093 controls) in the study. We found seasonal influenza vaccination to be an independent protective factor against hospitalizations owing to influenza [p < 0.01; odds ratio (OR), 0.427; 95% confidence interval (CI), 0.306–0.594]. Children with mean sun exposure time of >7 h/week had a significantly lower risk of influenza-related hospitalizations than those with the mean sun exposure time of ?7 h/week (p < 0.05; OR, 0.667; 95% CI, 0.491–0.906). Conclusions: Seasonal influenza vaccination effectively prevents influenza-related hospitalizations in children aged ?5 years. Besides, >7 h of sun exposure/week may also be associated with lower risk of influenza-related hospitalizations in children. ? 2019 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075460048&doi=10.1016%2fj.jmii.2019.09.010&partnerID=40&md5=ae6f51ff215459b116da7459b1212285 https://scholars.lib.ntu.edu.tw/handle/123456789/524976 |
ISSN: | 1684-1182 | DOI: | 10.1016/j.jmii.2019.09.010 | SDG/關鍵字: | influenza vaccine; probiotic agent; influenza vaccine; Article; breast feeding; case control study; child; child hospitalization; controlled study; dietary supplement; drug effect; educational status; female; hospital based case control study; hospital patient; human; infection risk; influenza A; influenza B; influenza vaccination; laboratory; major clinical study; male; mother; newborn care; preschool child; residential area; seasonal influenza; smoking; sun exposure; Taiwan; Taiwanese; time; treatment duration; hospitalization; immunology; infant; influenza; odds ratio; protection; season; statistical model; sunlight; vaccination; Case-Control Studies; Child, Preschool; Female; Hospitalization; Humans; Infant; Influenza Vaccines; Influenza, Human; Logistic Models; Male; Odds Ratio; Protective Factors; Seasons; Sunlight; Taiwan; Vaccination |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。