Unusual spinal cord lesions in late-onset non-ketotic hyperglycinemia
Journal
Journal of Child Neurology
Journal Volume
26
Journal Issue
7
Pages
900-903
Date Issued
2011
Author(s)
Abstract
Non-ketotic hyperglycinemia is a disorder of glycine metabolism with severe neurologic regression in the infantile stage, while late-onset non-ketotic hyperglycinemia is a rare form characterized by variable clinical, biochemical, and imaging features. This report describes a boy of late-onset non-ketotic hyperglycinemia presenting with an unusual long tract-like lesion of the spinal cord aside by magnetic resonance imaging. This is the first reported child of non-ketotic hyperglycinemia with abnormal imaging features of spinal cord. ? The Author(s) 2011.
SDGs
Other Subjects
glycine; amino acid blood level; article; case report; cerebrospinal fluid; child; corpus callosum; frontal gyrus; gait disorder; human; hyperglycinemia; leukodystrophy; male; medical history; medulla oblongata; nuclear magnetic resonance imaging; preschool child; priority journal; spinal cord lesion; white matter; Age of Onset; Child; Disease Progression; Humans; Hyperglycinemia, Nonketotic; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Spinal Cord; Spinal Cord Diseases
Type
journal article