Dilated Cardiomyopathy After Long-Term Right Ventricular Apical Pacing in Children With Complete Atrioventricular Block: Role of Setting of Ventricular Pacing
Journal
Journal of Cardiac Failure
Journal Volume
15
Journal Issue
8
Pages
681-688
Date Issued
2009
Author(s)
Wu K.-L.
Chiu H.-H.
Lue H.-C.
Abstract
Pediatric patients paced for complete atrioventricular block (CAVB) are at risk of developing dilated cardiomyopathy (DCM). We sought to explore the role played by the setting of ventricular pacing. A total of 35 patients 90% in all patients. Multivariate analysis revealed that the cumulative Z score of lower ventricular rate setting was the single most important risk factor for DCM (HR, 3.14; 95% CI, 1.07-9.19; P = .037). Subgroup analysis in patients with VVI/VVIR modes revealed an even stronger predictive value of the cumulative Z score of lower ventricular rate setting (HR, 9.12; 95% CI, 1.53-54.24; P = .015). Higher setting of the lower ventricular rate, though still within the age-appropriate range, was associated with increased risk of developing DCM in pediatric patients with CAVB and chronic RV apical pacing.
SDGs
Type
journal article