https://scholars.lib.ntu.edu.tw/handle/123456789/526890
標題: | Using the galectin-3 test to predict mortality in heart failure patients: A systematic review and meta-analysis | 作者: | Chen Y.-S. Gi W.-T. Liao T.-Y. Lee M.-T.G. Lee S.-H. Hsu W.-T. Chang S.-S. CHIEN-CHANG LEE |
公開日期: | 2016 | 卷: | 10 | 期: | 3 | 起(迄)頁: | 329-342 | 來源出版物: | Biomarkers in Medicine | 摘要: | Aim: Galectin-3 (Gal-3) is a new biomarker for assessing prognosis of heart failure (HF) patients. This systemic review and meta-analysis aims to examine Gal-3's ability in assessing prognosis of HF patients. Method: We searched MEDLINE and Embase up to November 2014. Test performance characteristics were summarized using forest plots and hierarchical summary receiver operating characteristic curves. Results: The diagnostic odds ratio of Gal-3 in predicting mortality in chronic HF patients was 2.36 (95% CI: 1.71-3.26) and 2.30 (95% CI: 1.76-3.01) in acute HF patients. Conclusion: Elevated levels of Gal-3 are associated with mortality in both acute and chronic HF patients. However, current evidence does not support sole use of Gal-3 for prognosis evaluation of HF patients. ? 2016 Future Medicine Ltd. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/526890 | ISSN: | 1752-0363 | DOI: | 10.2217/bmm.15.121 | SDG/關鍵字: | galectin 3; galectin 3; acute heart failure; death; diagnostic accuracy; diagnostic kit; ELISA kit; enzyme linked immunosorbent assay; heart failure; hospital readmission; human; mortality; prediction; prognosis; protein blood level; receiver operating characteristic; Review; sensitivity and specificity; systematic review; acute disease; chronic disease; heart failure; heart infarction; meta analysis; metabolism; Acute Disease; Chronic Disease; Galectin 3; Heart Failure; Humans; Myocardial Infarction |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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