https://scholars.lib.ntu.edu.tw/handle/123456789/527301
標題: | Correlation between age and allergens in pediatric atopic dermatitis | 作者: | Wang I.-J. YU-TSAN LIN YAO-HSU YANG CHI-LING CHEN Tsai Y.-H. BOR-LUEN CHIANG Hwang K.-C. |
公開日期: | 2004 | 出版社: | American College of Allergy, Asthma and Immunology | 卷: | 93 | 期: | 4 | 起(迄)頁: | 334-338 | 來源出版物: | Annals of Allergy, Asthma and Immunology | 摘要: | Background: There has been significant progress recently in the clinical investigation of atopic dermatitis (AD), especially in the recognition of aeroallergens as aggravating factors in AD. However, sensitization to food allergens and aeroallergens in children with AD has not been fully studied. Objective: To evaluate the correlation between age and allergens in children with AD. Methods: A retrospective cross-sectional study was performed between January 1, 1999, and December 31, 2002, on 262 children with a definitive diagnosis of AD aged 0 to 16 years. Comparison of 3 age groups (<2 years, 2-5 years, and >5 years) with the correlation of food allergens and aeroallergens using the CAP-FEIA test was made using linear regression and logistic regression analyses. Results: In children younger than 2 years, AD was associated with food allergens. In children aged 2 to 5 years, both food allergens and aeroallergens played an important role. In children older than 5 years, only elevated aeroallergen specific IgE levels were noted (P < .02). Age correlated negatively with food allergens and positively with aeroallergens after adjusting for sex (P < .04). Sensitization to aeroallergens may correlate with acquisition of the respiratory symptoms of the atopic state. Conclusions: Food allergens may be the major trigger of AD in early life, after which the role of environmental aeroallergens become more important and may be associated with respiratory sensitization. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-6044239441&doi=10.1016%2fS1081-1206%2810%2961391-9&partnerID=40&md5=192a55f44a227f366b504c8c9d3beaae https://scholars.lib.ntu.edu.tw/handle/123456789/527301 |
ISSN: | 1081-1206 | DOI: | 10.1016/S1081-1206(10)61391-9 | SDG/關鍵字: | allergen; immunoglobulin E; adolescent; article; atopic dermatitis; child; childhood disease; diagnostic test; human; infant; major clinical study; priority journal; retrospective study; sensitization; skin allergy; skin disease |
顯示於: | 醫學系 |
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