https://scholars.lib.ntu.edu.tw/handle/123456789/529259
標題: | State-of-the-art acute phase management of Kawasaki disease after 2017 scientific statement from the American Heart Association | 作者: | Liu Y.-C. MING-TAI LIN JOU-KOU WANG MEI-HWAN WU |
公開日期: | 2018 | 出版社: | Elsevier (Singapore) Pte Ltd | 卷: | 59 | 期: | 6 | 起(迄)頁: | 543-552 | 來源出版物: | Pediatrics and Neonatology | 摘要: | Kawasaki disease (KD) has become the most common form of pediatric systemic vasculitis. Although patients with KD received intravenous immunoglobulin (IVIG) therapy, coronary arterial lesions (CALs) still occurred in 5%–10% of these patients during the acute stage. CALs may persist and even progress to stenosis or obstruction. Therefore, CALs following KD are currently the leading cause of acquired heart diseases in children. The etiology of CALs remains unknown despite more than four decades of research. Two unsolved problems are IVIG unresponsiveness and the diagnosis of incomplete KD. The two subgroups of KD patients with these problems have a high risk of CAL. In April 2017, the American Heart Association (AHA) updated the guidelines for the diagnosis, treatment, and long-term management of KD. Compared with the previous KD guidelines published in 2004, the new guidelines provide solutions to the aforementioned two problems and emphasize risk stratification by using coronary artery Z score systems, as well as coronary severity–based management and long-term follow-up. Therefore, in this study, we merged the AHA Scientific Statement in 2017 with recent findings for Taiwanese KD patients to provide potential future care directions for Taiwanese patients with KD. ? 2018 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046161075&doi=10.1016%2fj.pedneo.2018.03.005&partnerID=40&md5=8c50d816d69bc54178347cfc1ef83027 https://scholars.lib.ntu.edu.tw/handle/123456789/529259 |
ISSN: | 1875-9572 | DOI: | 10.1016/j.pedneo.2018.03.005 | SDG/關鍵字: | acetylsalicylic acid; immunoglobulin; glucocorticoid; nonsteroid antiinflammatory agent; acute disease; adjuvant therapy; cardiovascular disease; coronary artery; follow up; human; mucocutaneous lymph node syndrome; practice guideline; Review; Taiwan; Taiwanese; coronary blood vessel; diagnostic imaging; echocardiography; mucocutaneous lymph node syndrome; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vessels; Echocardiography; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Mucocutaneous Lymph Node Syndrome; Practice Guidelines as Topic |
顯示於: | 醫學系 |
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