https://scholars.lib.ntu.edu.tw/handle/123456789/529911
標題: | Spontaneous pneumothorax associated with ankylosing spondylitis | 作者: | CHIEN-CHANG LEE Lee S.-H. Chang I.-J. TSUNG-CHIEN LU ANG YUAN Chang T.-A. Tsai K.-C. WEN-JONE CHEN |
公開日期: | 2005 | 卷: | 44 | 期: | 12 | 起(迄)頁: | 1538-1541 | 來源出版物: | Rheumatology | 摘要: | Objective. To review the incidence and clinical characteristics of spontaneous pneumothorax in patients with ankylosing spondylitis (AS). Methods. This is a retrospective observational cohort study. Chest radiographs and medical records of patients with a diagnosis of AS from 1993 to 2003 in a tertiary referral centre were reviewed. Results. A total of 1028 patients with a diagnosis of AS were identified from July 1993 to July 2003. Twenty-two patients had typical apical lung fibrotic changes in the chest radiographs (22/1028, 2.1%). Three of these patients (3/22, 13.6%) with lung disease had pneumothorax. Two patients had recurrences and received video-assisted thoracoscopic surgery (VATS) on the second attack. The third patient received talc pleurodesis on the first attack and did not have a recurrence. The incidence of spontaneous pneumothorax in patients with AS was 0.29% (3/1028) with an incidence density of 64.85/100000 patient-yr (95% confidence interval: 66.17-63.57/100000). Conclusion. Spontaneous pneumothorax appears to be exceedingly rare in AS unless there is an underlying fibrocystic lung disease, in which case its occurrence is not uncommon. Cigarette smoking may be an important co-factor. Once developed, recurrences are common even after treatment. Prophylactic procedures should thus be considered for the first attack of spontaneous pneumothorax. ? The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/529911 | ISSN: | 1462-0324 | DOI: | 10.1093/rheumatology/kei077 | SDG/關鍵字: | adult; aged; ankylosing spondylitis; cigarette smoking; clinical feature; confidence interval; controlled study; disease association; human; incidence; lung surgery; major clinical study; male; medical record; pleurodesis; priority journal; prophylaxis; rare disease; recurrent disease; retrospective study; review; spontaneous pneumothorax; thoracoscopy; thoracotomy; thorax radiography; Adult; Aged; Female; Humans; Male; Middle Aged; Pneumothorax; Pulmonary Fibrosis; Recurrence; Retrospective Studies; Smoking; Spondylitis, Ankylosing; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。