https://scholars.lib.ntu.edu.tw/handle/123456789/530035
標題: | Dobutamine Stress Echocardiography for Detecting Coronary Artery Disease | 作者: | CHAU-CHUNG WU YI-LWUN HO Kao S.-L. WEN-JONE CHEN CHII-MING LEE MING-FONG CHEN Liau C.-S. Lee Y.-T. |
公開日期: | 1996 | 卷: | 87 | 期: | 3 | 起(迄)頁: | 244-249 | 來源出版物: | Cardiology (Switzerland) | 摘要: | To assess the value of dobutamine stress echocardiography (DSE) to detect coronary artery disease (CAD) and to compare the diagnostic accuracy between DSE and treadmill exercise test (TXT), 104 patients (mean age 58 ± 12 years) presenting for coronary angiography were prospectively studied. TXT was performed according to the Bruce protocol. Dobutamine (5-40 μg/ kg/min) was infused in 3-min stages. Digital echocardiograms were recorded on-line at baseline, during low- and peak-dose dobutamine infusion, and at recovery. An echocardiogram positive for CAD was defined as the one showing a new wall motion abnormality (WMA) induced by dobutamine. There were no major complications during the study. Significant CAD (≧ 50% diameter stenosis) was present in 17 of 30 patients who had normal echocardiograms at baseline. The sensitivity for detecting CAD was 76% by TXT and 94% by DSE, and the specificity was only 38% by TXT and 92% by DSE, respectively. Seventy-four patients had localized rest WMAs. Twenty-four had no significant CAD or lesions only confined to regions with abnormal rest wall motion, and 50 had disease remote from these regions. The sensitivity for detection of remote disease was 60% by TXT and 76% by DSE, and the specificity was 75% by TXT and 96% by DSE, respectively. In conclusion, DSE is a safe and accurate diagnostic tool for identifying CAD and for predicting the extent of disease in those who have localized rest WMAs. ? 1996 S. Karger AG, Basel. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/530035 | ISSN: | 0008-6312 | DOI: | 10.1159/000177095 | SDG/關鍵字: | dobutamine; adult; aged; angiocardiography; article; clinical trial; controlled clinical trial; controlled study; coronary artery disease; diagnostic accuracy; dobutamine stress echocardiography; echocardiography; exercise electrocardiography; female; heart function test; heart hemodynamics; heart rate; human; intermethod comparison; major clinical study; male; priority journal; stenosis; stress echocardiography; systolic blood pressure; treadmill exercise |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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