https://scholars.lib.ntu.edu.tw/handle/123456789/530307
標題: | Longitudinal follow-up of lymphocyte subsets during the first year of life | 作者: | PO-NIEN TSAO BOR-LUEN CHIANG YAO-HSU YANG Tsai M.-J. FRANK LEIGH LU HUNG-CHIEH CHOU Tsou K.-I. |
公開日期: | 2002 | 卷: | 20 | 期: | 3 | 起(迄)頁: | 147-153 | 來源出版物: | Asian Pacific Journal of Allergy and Immunology | 摘要: | A longitudinal study of lymphocyte subsets during infancy was evaluated by using the flow cytometric immunophenotyping method. Two hundred and thirteen blood samples were obtained from 92 healthy, full-term infants of the following ages: 1-7 days old (n = 43), 3 months old (n = 55), 6 months old (n = 57) and 11 months old (n = 58). The absolute numbers of CD3+ and CD3+/CD4+ T lymphocytes increased from birth to 3 months of age, and remained stable thereafter. The absolute number of CD3+/CD8+ T lymphocytes increased from birth to 11 months of age. The absolute number of CD19+ B lymphocytes and NK cells increased rapidly (3 months) after birth and continued to increase throughout the study period. However, the changes in the relative counts of lymphocyte subsets did not always correspond with the changes in their absolute numbers. These results demonstrate the age-related changes in lymphocyte subpopulations and provide reference ranges for lymphocyte subsets during infancy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036771398&partnerID=40&md5=3c8f9dd159fece972962197ef2fab4cb https://scholars.lib.ntu.edu.tw/handle/123456789/530307 |
ISSN: | 0125-877X | SDG/關鍵字: | age; article; B lymphocyte; blood sampling; cell count; controlled study; female; flow cytometry; follow up; human; human cell; immunophenotyping; infant; longitudinal study; lymphocyte count; lymphocyte subpopulation; male; natural killer cell; outcomes research; reference value; T lymphocyte; Age Factors; Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Female; Follow-Up Studies; Gestational Age; Humans; Infant; Infant Welfare; Infant, Newborn; Killer Cells, Natural; Longitudinal Studies; Lymphocyte Count; Lymphocyte Subsets; Male; Reference Values; Sex Factors; T-Lymphocytes; Taiwan |
顯示於: | 醫學系 |
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