Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Factors associated with the prescription of inhaled corticosteroids in GOLD group A and B patients with COPD – Subgroup analysis of the Taiwan obstructive lung disease cohort
 
  • Details

Factors associated with the prescription of inhaled corticosteroids in GOLD group A and B patients with COPD – Subgroup analysis of the Taiwan obstructive lung disease cohort

Journal
International Journal of COPD
Journal Volume
10
Journal Issue
1
Pages
1951-1956
Date Issued
2015
Author(s)
Wei Y.-F.
PING-HUNG KUO  
Tsai Y.-H.
Tao C.-W.
Cheng S.-L.
Lee C.-H.
Wu Y.-K.
Chen N.-H.
Hsu W.-H.
Hsu J.-Y.
Lin M.-S.
Wang C.-C.
DOI
10.2147/COPD.S88114
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941889823&doi=10.2147%2fCOPD.S88114&partnerID=40&md5=c01b345a56e6502d94ad102046b778a3
https://scholars.lib.ntu.edu.tw/handle/123456789/530837
Abstract
Background and objective: The overprescription of inhaled corticosteroids (ICS) in the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) group A and B patients with chronic obstructive pulmonary disease (COPD) is not uncommon in clinical practice. The aim of this study was to explore the factors associated with the use of ICS in these patients. Methods: The Taiwan obstructive lung disease (TOLD) study was a retrospective, observational nationwide survey of COPD patients conducted at 12 hospitals (n=1,096) in Taiwan. Multivariate logistic regression models were used to explore the predictors of ICS prescription in GOLD group A and B patients. Results: Among the group A (n=179) and group B (n=398) patients, 198 (34.3%) were prescribed ICS (30.2% in group A and 36.2% in group B, respectively). The wheezing phenotype was present in 28.5% of group A and 34.2% of group B patients. Wheezing was the most significant factor for an ICS prescription in group A (odds ratio [OR], 2.33; 95% confidence interval [CI], 1.14-4.75; P=0.020), group B (OR, 1.93; 95% CI, 1.24-2.99; P=0.004), and overall (OR, 2.04; 95% CI, 1.40-2.96; P<0.001). The COPD assessment test score was also associated with an ICS prescription in group B (OR, 1.04; 95% CI, 1.00-1.07; P=0.038). Conclusion: About one-third of the GOLD group A and B patients with COPD in Taiwan are prescribed ICS. Our findings suggest that wheezing and COPD assessment test score are related to the prescription of ICS in these patients. ? 2015 Wei et al.
SDGs

[SDGs]SDG3

Other Subjects
corticosteroid; bronchodilating agent; corticosteroid; adult; Article; chronic obstructive lung disease; COPD assessment test; drug utilization; female; human; major clinical study; male; observational study; prescription; respiratory tract disease assessment; retrospective study; risk factor; Taiwan; wheezing; abnormal respiratory sound; aged; classification; inhalational drug administration; middle aged; multivariate analysis; odds ratio; pathophysiology; Pulmonary Disease, Chronic Obstructive; severity of illness index; statistical model; very elderly; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pulmonary Disease, Chronic Obstructive; Respiratory Sounds; Retrospective Studies; Severity of Illness Index; Taiwan
Publisher
Dove Medical Press Ltd.
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science