https://scholars.lib.ntu.edu.tw/handle/123456789/530960
標題: | Assessment of the coronary artery disease and systolic dysfunction in hypertensive patients with the dobutamine-atropine stress echocardiography: Effect of the left ventricular hypertrophy | 作者: | YI-LWUN HO CHAU-CHUNG WU Lin, Lung-Chun CHIEN-HUA HUANG WEN-JONE CHEN MING-FONG CHEN Liau, Chiau-Suong Lee, Yuang-Teh |
公開日期: | 1997 | 出版社: | S. Karger AG | 卷: | 89 | 期: | 1 | 起(迄)頁: | 52-58 | 來源出版物: | Cardiology | 摘要: | This study was performed to evaluate whether left ventricular hypertrophy (LVH) can influence the diagnostic accuracy of coronary artery disease (CAD) using the dobutamine stress echocardiography (DSE) in hypertensive patients. In addition to the detection of CAD, the relationship between systolic dysfunction and the quantitation wall motion scoring system of DSE was studied also. DSE was performed in 101 patients. There were 45 (45%) patients with a history of acute myocardial infarction. Twenty-eight patients (28%) had electrocardiographic LVH and 59 patients (58%) had echocardiographic LVH. A total of 74 patients (73%) had angiographically documented CAD defined as ? 50% diameter stenosis. For the 56 patients without history of myocardial infarction, the diagnostic sensitivity, specificity, and accuracy in detecting CAD were not influenced by LVH defined by either electrocardiography or echocardiography. For the total patients, the diagnostic sensitivity, specificity, and accuracy in detecting multivessel disease were also not influenced by LVH defined by either method. The resting global wall motion score was correlated well with the left ventricular ejection fraction in patients with and without LVH (r = -0.70, p < 0.001 vs. r = -0.70, p < 0.001). When using the resting wall motion score of 24 as a cutoff value, the diagnostic sensitivity, specificity, and accuracy of systolic dysfunction (defined by left ventricular ejection fraction < 40%) were 79, 86 and 85%, respectively. In conclusion, the diagnostic accuracy of CAD using the DSE was not affected by LVH in hypertensive patients. In addition to detection of coronary artery disease, the resting wall motion score of DSE was able to detect systolic dysfunction in patients with and without LVH. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030778415&doi=10.1159%2f000006743&partnerID=40&md5=9a1269b979a467d9178491e09beba868 https://scholars.lib.ntu.edu.tw/handle/123456789/530960 |
ISSN: | 0008-6312 | DOI: | 10.1159/000006743 | SDG/關鍵字: | atropine; dobutamine; cardiotonic agent; diagnostic agent; dobutamine; acute heart infarction; adult; aged; article; coronary artery disease; coronary artery obstruction; diagnostic accuracy; diagnostic value; echocardiography; exercise electrocardiography; female; heart left ventricle ejection fraction; heart left ventricle hypertrophy; human; hypertension; intravenous drug administration; major clinical study; male; priority journal; scoring system; coronary artery disease; echography; exercise test; heart left ventricle function; heart stroke volume; hypertension; middle aged; pathophysiology; roc curve; sensitivity and specificity; systole; Aged; Atropine; Cardiotonic Agents; Coronary Disease; Dobutamine; Exercise Test; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; ROC Curve; Sensitivity and Specificity; Stroke Volume; Systole; Ventricular Dysfunction, Left |
顯示於: | 醫學系 |
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