Next-generation sequencing identifies TRPV4-related skeletal dysplasia in a boy with progressive bowlegs
Journal
Pediatrics and Neonatology
Journal Volume
60
Journal Issue
1
Pages
102-104
Date Issued
2019
Author(s)
Chen M.
Chung I.-F.
Chen C.-Y.
Cheng W.-C.
Abstract
Angular deformities of the lower limbs are common during childhood. In children under 2 years of age, bowleg (genu varum) may represent a normal physiological process. In certain circumstances, pathologic bowlegs result from Blount disease, rickets and other metabolic bone diseases, skeletal dysplasia, asymmetric growth secondary to infection, trauma and neoplasia even in a child without a family history.1
Publisher
Elsevier (Singapore) Pte Ltd
Type
journal article