https://scholars.lib.ntu.edu.tw/handle/123456789/531800
標題: | Microalbuminuria screening for detecting chronic kidney disease in the general population: A systematic review | 作者: | Wu H.-Y. JENQ-WEN HUANG Peng Y.-S. KUAN-YU HUNG KWAN-DUN WU Lai M.-S. KUO-LIONG CHIEN |
公開日期: | 2013 | 卷: | 35 | 期: | 5 | 起(迄)頁: | 607-614 | 來源出版物: | Renal Failure | 摘要: | Background: Microalbuminuria screening is widely used in high-risk populations but seldom used in the general population for detecting chronic kidney disease (CKD). Systematic reviews focused on screening for CKD are rare, and the issues about microalbuminuria screening in the general population have never been reviewed. We systematically reviewed studies regarding microalbuminuria screening and evaluated the benefits and harms of this screening method in the general population. Methods: We systematically searched MEDLINE, PubMed, and the Cochrane Library for English articles published from January 1970 to 13 December 2011. Quality assessments were performed using the QUADAS tool or the Drummond's 10-point checklist. Due to the high heterogeneity of the study designs, meta-analysis for the study results was not possible. Therefore, we performed a narrative synthesis. Results: Six articles from four studies made up our final study population, with four articles evaluating different screening methodologies and two reporting cost-effectiveness analyses. The qualities of the included articles ranged from fair to high. Spot urine albumin concentration and spot urine albumin:creatinine ratio had a similar diagnostic performance for microalbuminuria screening in the general population. Screening for microalbuminuria in high-risk populations, such as patients with diabetes, hypertension, or old age, was cost-effective. However, there was no consensus regarding the cost-effectiveness for microalbuminuria screening in the general population. Conclusions: Microalbuminuria screening in high-risk populations is cost-effective. However, the cost-effectiveness of screening for microalbuminuria in the general population deserves further study. To keep costs low, spot urine albumin concentration may be preferable than the albumin:creatinine ratio. Copyright ? 2013 Informa Healthcare USA, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877858622&doi=10.3109%2f0886022X.2013.779907&partnerID=40&md5=71655ef4c740fc5e2eab499164391dcb https://scholars.lib.ntu.edu.tw/handle/123456789/531800 |
ISSN: | 0886-022X | DOI: | 10.3109/0886022X.2013.779907 | SDG/關鍵字: | albumin; creatinine; chronic kidney disease; cost effectiveness analysis; diabetes mellitus; diagnostic accuracy; high risk population; human; hypertension; macroalbuminuria; mass screening; microalbuminuria; patient selection; population; priority journal; quality control; quality of life; randomized controlled trial (topic); review; senescence; systematic review; Albuminuria; Humans; Mass Screening; Renal Insufficiency, Chronic |
顯示於: | 醫學系 |
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