|Title:||Application of speckle-tracking echocardiography in detecting coronary artery disease in patients with maintenance hemodialysis||Authors:||Liu Y.-W.
|Issue Date:||2011||Journal Volume:||32||Journal Issue:||1||Start page/Pages:||38-42||Source:||Blood Purification||Abstract:||
Background: Satisfactory and noninvasive diagnostic tools for coronary artery disease (CAD) are not available in hemodialysis patients. We aimed to elucidate a reliable tool to diagnose CAD in these patients. Methods: 102 hemodialysis patients received 2D speckle-tracking echocardiography with left ventricular (LV) strain analysis and blood tests for cardiac troponin T, high-sensitive C-reactive protein, interleukin (IL)-6, and IL-18. Results: The levels of biomarkers did not differ between patients with and without CAD. The factors associated with CAD were decreased circumferential strain, decreased global longitudinal strain, and the number of LV segments with decreased longitudinal strain. Logistic regression analyses showed that the number of LV segments with decreased longitudinal strain, over 6 segments, was strongly associated with CAD in hemodialysis patients (OR 12.08, 95% CI 3.724-39.209). Conclusions: The noninvasive modality of speckle-tracking echocardiography with strain analysis is efficient and objective for identifying CAD in hemodialysis patients. ? 2011 S. Karger AG, Basel.
|ISSN:||0253-5068||DOI:||10.1159/000323536||metadata.dc.subject.other:||C reactive protein; interleukin 18; interleukin 6; troponin T; article; blood analysis; coronary artery disease; diagnostic value; echocardiography; heart left ventricle; hemodialysis patient; human; major clinical study; predictive value; priority journal; risk factor; Aged; C-Reactive Protein; Coronary Artery Disease; Echocardiography; Female; Heart Ventricles; Humans; Image Interpretation, Computer-Assisted; Interleukin-18; Interleukin-6; Longitudinal Studies; Male; Middle Aged; Renal Dialysis; Renal Insufficiency, Chronic; Taiwan; Troponin T; Ventricular Dysfunction, Left
|Appears in Collections:||醫學系|
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