2018 expert consensus on the management of adverse effects of antiplatelet therapy for acute coronary syndrome in Taiwan
Journal
Acta Cardiologica Sinica
Journal Volume
34
Journal Issue
3
Pages
201-210
Date Issued
2018
Author(s)
Li Y.-H.
Fang C.-Y.
Hsieh I.-C.
Huang W.-C.
Lin T.-H.
Sung S.-H.
Chiu C.-Z.
Wu C.-J.
Shyu K.-G.
Fang C.-C.
Lu T.-M.
Chen C.-P.
Tai W.-C.
Sheu C.-C.
Wei K.-C.
Huang Y.-H.
Wu H.-M.
Abstract
Antiplatelet therapy is a key component in the treatment of acute coronary syndrome (ACS). The management of ACS has evolved considerably over recent years with the development of new and more potent antiplatelet agents. Clinical trials on ACS have demonstrated that potent antiplatelet agents can more effectively reduce cardiovascular events. However, there is a tipping point between safety and efficacy, beyond which the risk of bleeding and other adverse effects can outweigh the benefits of antiplatelet therapy. Striking a balance between safety and efficacy remains a major challenge. A consensus meeting of an expert panel composed of Taiwanese experts was held to provide recommendations for the management of adverse effects in patients with ACS receiving antiplatelet therapy. The common adverse effects of antiplatelet therapy include upper gastrointestinal bleeding, ecchymosis, hematuria, epistaxis and ticagrelor-related dyspnea. In this study, a literature review of these adverse events was performed and recommendations for the management were made. ? 2018, Republic of China Society of Cardiology. All rights reserved.
SDGs
Other Subjects
acetylsalicylic acid; antithrombocytic agent; clopidogrel; ticagrelor; acute coronary syndrome; acute heart infarction; bleeding; brain hemorrhage; cardiovascular disease; cerebrovascular accident; dual antiplatelet therapy; dyspnea; ecchymosis; epistaxis; gastrointestinal hemorrhage; hematuria; hemopericardium; hemoptysis; human; intraocular hemorrhage; perforation; randomized controlled trial (topic); retroperitoneal hemorrhage; Review; risk factor; Taiwan; treatment outcome; ulcer; upper gastrointestinal bleeding
Publisher
Republic of China Society of Cardiology
Type
review