Clostridium difficile infection in a patient with Crohn disease
Journal
Journal of the Formosan Medical Association
Journal Volume
111
Journal Issue
6
Pages
347-349
Date Issued
2012
Author(s)
Abstract
Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown. The authors report on a 14-year-old girl with Crohn disease who has acute gastrointestinal symptoms caused by toxin A-producing . Clostridium difficile, which mimicked a flare-up of Crohn disease. There was no preceding antibiotic prescription before the episode. The disease activity did not improve after steroid treatment, which is unusual for Crohn disease. However, all symptoms were dramatically relieved after eradication of . C difficile, and led to a symptom-free period for more than 3 years. This case report aims to address the unusual presentation of a usual pathogen, . C difficile, in a pediatric patient with Crohn disease. ? 2012.
SDGs
Other Subjects
albumin; azathioprine; ciprofloxacin; Clostridium difficile toxin A; mercaptopurine; mesalazine; metronidazole; prednisolone; vancomycin; abdominal pain; acute disease; adolescent; albumin blood level; anemia; article; bloody diarrhea; case report; cell infiltration; Clostridium difficile infection; colon mucosa; colonoscopy; Crohn disease; crypt cell; disease activity; disease exacerbation; drug substitution; drug withdrawal; enzyme immunoassay; erythrocyte sedimentation rate; esophagogastroduodenoscopy; feces culture; female; fever; gastrointestinal symptom; hematochezia; histopathology; human; human tissue; immunosuppressive treatment; intestine polyp; intestine ulcer; lamina propria; leukocyte aggregation; recurrent disease; submucosa; Adolescent; Clostridium difficile; Clostridium Infections; Crohn Disease; Disease Progression; Female; Humans
Type
journal article