https://scholars.lib.ntu.edu.tw/handle/123456789/535431
標題: | A novel combination regimen for the treatment of refractory bacteremia due to multidrug-resistant Pseudomonas aeruginosa in a liver transplant recipient | 作者: | HSIN-YUN SUN Shields R.K. Cacciarelli T.V. Muder R.R. Singh N. |
公開日期: | 2010 | 卷: | 12 | 期: | 6 | 起(迄)頁: | 555-560 | 來源出版物: | Transplant Infectious Disease | 摘要: | Both bacteremia and biliary cast syndrome are serious post-transplant complications in liver transplant recipients. In the setting of increasing drug resistance in the current era, management of infections caused by multidrug-resistant (MDR) bacteria has proven challenging. We present a case of a liver transplant recipient who developed biliary cast syndrome and intractable MDR Pseudomonas bacteremia that failed to resolve with conventional antimicrobial therapy and which was finally controlled by a novel combination regimen of colistimethate, doripenem, and tobramycin. Future studies validating the clinical efficacy of this combination strategy are warranted. ? 2010 John Wiley & Sons A/S. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650083100&doi=10.1111%2fj.1399-3062.2010.00543.x&partnerID=40&md5=4c20475fbc3a843d9e5507fddd33def6 https://scholars.lib.ntu.edu.tw/handle/123456789/535431 |
ISSN: | 1398-2273 | DOI: | 10.1111/j.1399-3062.2010.00543.x | SDG/關鍵字: | ciprofloxacin; colistimethate; doripenem; piperacillin plus tazobactam; prednisone; rifampicin; tacrolimus; tobramycin; adult; antibiotic sensitivity; article; bacteremia; biliary cast syndrome; biliary tract disease; biliary tract drainage; case report; chronic kidney disease; diabetes mellitus; drug withdrawal; follow up; graft recipient; hepatitis C; human; liver cell carcinoma; liver cirrhosis; liver graft; liver graft rejection; liver transplantation; male; multidrug resistance; nonhuman; priority journal; Pseudomonas aeruginosa; renal replacement therapy; retransplantation; Anti-Bacterial Agents; Bacteremia; Bile Duct Diseases; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Liver Transplantation; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome |
顯示於: | 醫學系 |
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