Healthcare-associated outbreak due to pan-drug resistant Acinetobacter baumannii in a surgical intensive care unit
Journal
Journal of Hospital Infection
Journal Volume
53
Journal Issue
2
Pages
97-102
Date Issued
2003
Author(s)
Wang S.H.
Chang Y.Y.
Wang L.H.
Lin H.C.
Chen M.L.
Pan H.J.
Ko W.J.
Lin F.Y.
Abstract
Acinetobacter baumannii is ubiquitous and has recently become one of the most important healthcare-associated (HA) pathogens in hospitals. Infection caused by this organism often leads to significant morbidity and mortality. Outbreaks of pan-drug resistant Acinetobacter baumannii (PDRAB) have rarely been reported. During a two-month period, an outbreak of PDRAB colonization and infection affecting 7 patients occurred in our surgical intensive care unit (SICU). The colonized sites were respiratory tract (N =7) and central venous catheter (N =2). One of the patients had a surgical wound infection. Extensive environmental contamination was identified, including sites such as bed rails, bedside tables, surface of ventilators and infusion pump, water for nasogastric feeding and ventilator rinsing and sinks. All of the isolates were analysed by pulsed-field gel electrophoresis (PFGE) and showed an identical pattern. After use of strict cohort nursing, hand hygiene environmental cleaning, and replacement of a dysfunctional high-efficiency particulate air filter (HEPA), the outbreak was controlled. ? 2003 The Hospital Infection Society.
SDGs
Other Subjects
amikacin; aztreonam; cefpirome; ceftazidime; ciprofloxacin; flomoxef; gatifloxacin; gentamicin; imipenem; meropenem; minocycline; moxifloxacin; piperacillin; piperacillin plus tazobactam; sultamicillin; ticarcillin; timentin; Acinetobacter baumannii; adult; aged; antibiotic resistance; article; bacterial colonization; bacterium contamination; bacterium isolation; central venous catheter; cleaning; clinical article; controlled study; epidemic; female; hand washing; hospital hygiene; hospital infection; human; intensive care unit; male; morbidity; mortality; personal hygiene; pulsed field gel electrophoresis; respiratory system; risk factor; surgical infection; surgical ward; bacterial infection; central venous catheterization; drug effect; epidemic; equipment; isolation and purification; microbiological examination; middle aged; pathogenicity; Taiwan; Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Catheterization, Central Venous; Disease Outbreaks; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Equipment Contamination; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Taiwan
Type
journal article