https://scholars.lib.ntu.edu.tw/handle/123456789/536570
標題: | Amiodarone-related pneumonitis | 作者: | SHENG-NAN CHANG HWANG, JUEY-JEN Hsu K.-L. CHIA-TI TSAI LING-PING LAI JIUNN-LEE LIN Tseng C.-D. FU-TIEN CHIANG |
公開日期: | 2007 | 出版社: | Scientific Communications International Ltd | 卷: | 106 | 期: | 5 | 起(迄)頁: | 411-417 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Amiodarone-related pneumonitis is a potentially limiting factor for amiodarone usage. However, it is believed that amiodarone-related pneumonitis is unlikely to occur during low-dose and short courses of therapy. We report three patients who received low-dose amiodarone, 200 mg/day, for an average of 6.6 months and who developed amiodarone-related pneumonitis. All patients were male with age of 75, 93 and 85, respectively, and had the habit of cigarette smoking. The initial presentation was dyspnea without symptoms and signs of heart failure. Their chest radiographs showed diffuse interstitial pneumonitis pattern and chest computed tomography scan also confirmed interstitial pneumonitis. Treatment included cessation of amiodarone and corticosteroid usage. All patients improved symptomatically by early detection and early treatment. This case report implies that old age and possible pre-existing pulmonary abnormalities caused by smoking could be associated with amiodarone-related pulmonary toxicity. Clinicians must remain alert to detect amiodarone-related pneumonitis even under low dosage and short duration of amiodarone usage. Immediate withdrawal of amiodarone and prompt steroid therapy will ensure full recovery. ? 2007 Elsevier & Formosan Medical Association. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250626045&doi=10.1016%2fS0929-6646%2809%2960328-4&partnerID=40&md5=49d6e8500c4ffed9df8a7cf07d35899d https://scholars.lib.ntu.edu.tw/handle/123456789/536570 |
ISSN: | 0929-6646 | DOI: | 10.1016/S0929-6646(09)60328-4 | SDG/關鍵字: | amiodarone; corticosteroid; methylprednisolone sodium succinate; prednisolone; sultamicillin; aged; aging; article; case report; cigarette smoking; computer assisted tomography; drug dose reduction; drug use; drug withdrawal; dyspnea; early diagnosis; early intervention; female; heart failure; human; interstitial pneumonia; low drug dose; lung disease; lung toxicity; short course therapy; steroid therapy; thorax radiography; treatment duration |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。