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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/536708
Title: Preoperative plasma N-terminal pro-brain natriuretic peptide as a marker of cardiac risk in patients undergoing elective non-cardiac surgery
Authors: Yeh H.-M.
Lau H.-P.
Lin J.-M.
WEI-ZEN SUN 
MING-JIUH WANG 
LING-PING LAI 
Issue Date: 2005
Journal Volume: 92
Journal Issue: 8
Start page/Pages: 1041-1045
Source: British Journal of Surgery
Abstract: 
Background: Plasma N-terminal pro-brain natriuretic peptide (NTproBNP) is a sensitive marker for heart failure. This study tested whether the preoperative plasma level of NTproBNP could predict cardiac complications in patients undergoing non-cardiac surgery. Methods: A total of 190 consecutive patients who underwent elective non-cardiac surgery that required general anaesthesia were studied. In addition to routine preoperative evaluation, a blood sample was taken for estimation of plasma NTproBNP concentration. Postoperative cardiac complications were defined as cardiac death, acute coronary syndrome, heart failure and haemodynamic compromise from cardiac arrhythmias. Results: Fifteen of the 190 patients had a cardiac complication: four had acute coronary syndrome and 13 had congestive heart failure. NTproBNP concentration was significantly higher in patients with a cardiac complication; a level greater than 450 ng/l was predictive of cardiac complications with a sensitivity of 100 per cent and a specificity of 82-9 per cent. Other factors associated with cardiac complications were a higher American Society of Anesthesiologists grade, age and clinical cardiac impairment, but in a multivariate analysis NTproBNP level was the only independent factor. Conclusion: Preoperative plasma NTproBNP concentration may be an independent predictor of cardiac complications in patients undergoing non-cardiac surgery. Copyright ? 2005 British Journal of Surgery Society Ltd.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-23844499720&doi=10.1002%2fbjs.4947&partnerID=40&md5=45dea127ac9c8c7e037ce46ae6f40e8a
https://scholars.lib.ntu.edu.tw/handle/123456789/536708
ISSN: 0007-1323
DOI: 10.1002/bjs.4947
SDG/Keyword: brain natriuretic peptide; adult; article; blood analysis; cardiovascular risk; concentration response; congestive heart failure; controlled study; disease marker; elective surgery; female; general anesthesia; heart arrhythmia; heart death; heart failure; heart muscle ischemia; hemodynamics; human; major clinical study; male; multivariate analysis; postoperative complication; preoperative evaluation; priority journal; protein blood level; Atrial Natriuretic Factor; Biological Markers; Female; Heart Diseases; Humans; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; Preoperative Care; Protein Precursors; Risk Factors; Surgical Procedures, Elective
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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