https://scholars.lib.ntu.edu.tw/handle/123456789/536942
標題: | A review of strategies to prevent mother-to-infant transmission of hepatitis B virus infection | 作者: | Wen W.-H. Lai M.-W. MEI-HWEI CHANG |
關鍵字: | HBV DNA; hepatitis B immunoglobulin; hepatitis B vaccine; immunoprophylactic failure; nucleoside/nucleotide analogue | 公開日期: | 2016 | 出版社: | Taylor and Francis Ltd | 卷: | 10 | 期: | 3 | 起(迄)頁: | 317-330 | 來源出版物: | Expert Review of Gastroenterology and Hepatology | 摘要: | Hepatitis B virus (HBV) infection causes long-term, life-threatening liver diseases worldwide. HBV is transmitted through either the horizontal or mother-to-infant route, which is the major route of transmission in endemic areas. Administration of hepatitis B immunoglobulin and hepatitis B vaccine to newborns of infected mothers prevents mother-to-infant transmission. Implementation of a universal hepatitis B vaccination program has proven successful in eliminating the infection and related complications. Nevertheless, efforts are still needed to improve global coverage of the hepatitis B vaccine. Infants born to highly viremic mothers are still at risk of infection despite current immunoprophylaxis. An increasing number of reports have shown promising efficacy and safety profiles with the use of nucleoside/nucleotide analogues in highly viremic pregnant women to prevent mother-to-infant transmission. ? 2015 Taylor & Francis. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959096094&doi=10.1586%2f17474124.2016.1120667&partnerID=40&md5=17eca0b2afdc93c9101cb983986910d5 https://scholars.lib.ntu.edu.tw/handle/123456789/536942 |
ISSN: | 1747-4124 | DOI: | 10.1586/17474124.2016.1120667 | SDG/關鍵字: | hepatitis B antibody; hepatitis B surface antigen; hepatitis B vaccine; hepatitis B(e) antigen; nucleoside derivative; nucleotide derivative; antivirus agent; hepatitis B hyperimmune globulin; hepatitis B vaccine; immunoglobulin; active immunization; breast feeding; cesarean section; drug efficacy; drug safety; endemic disease; gene; gene mutation; health care availability; health care quality; hepatitis B; Hepatitis B virus; human; immunization; immunoprophylaxis; infection risk; nonhuman; obstetric procedure; passive immunization; pregnancy complication; pregnant woman; prenatal care; preventive health service; resource allocation; Review; risk factor; surface gene; vaginal delivery; vertical transmission; viremia; virus inhibition; virus load; virus transmission; female; genetics; genotype; hepatitis B; Hepatitis B virus; newborn; pathogenicity; phenotype; pregnancy; prevention and control; transmission; treatment outcome; vertical transmission; Antiviral Agents; Female; Genotype; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; Humans; Immunoglobulins; Infant, Newborn; Infectious Disease Transmission, Vertical; Phenotype; Pregnancy; Risk Factors; Treatment Outcome |
顯示於: | 醫學系 |
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