The development of hepatocellular carcinoma among prospectively followed children with chronic hepatitis B virus infection
Journal
Journal of Pediatrics
Journal Volume
144
Journal Issue
3
Pages
397-399
Date Issued
2004
Author(s)
Abstract
We prospectively followed 426 children with chronic hepatitis B virus infection. During 6250 person-years, 2 boys developed hepatocellular carcinoma, with an incidence of 32 per 100,000 person-years. Both had e antigen seroconversion in early childhood and cirrhosis. Early e antigen seroconversion and/or cirrhosis may be risk factors for hepatocellular carcinoma.
SDGs
Other Subjects
adolescent; adult; article; child; controlled study; disease course; female; hepatitis B; Hepatitis B virus; human; incidence; liver cell carcinoma; liver cirrhosis; major clinical study; male; priority journal; risk factor; seroconversion
Publisher
Mosby Inc.
Type
journal article