https://scholars.lib.ntu.edu.tw/handle/123456789/537128
標題: | The diagnostic value of sensory evoked potentials in pediatric Wilson disease | 作者: | Hsu Y.-S. Chang Y.-C. WANG-TSO LEE YEN-HSUAN NI HONG-YUAN HSU MEI-HWEI CHANG |
公開日期: | 2003 | 出版社: | Elsevier Inc. | 卷: | 29 | 期: | 1 | 起(迄)頁: | 42-45 | 來源出版物: | Pediatric Neurology | 摘要: | We studied the sensory evoked potentials in pediatric Wilson disease to verify their subclinical neurologic involvement and to elucidate the role of cirrhosis in abnormal evoked potentials in non-neurologic Wilson disease. Thirty children (17 male, 13 female), diagnosed with Wilson disease before 18 years, were enrolled. The mean age during studies was 15.8 ± 6.3 years, and disease duration since diagnosis was 3.0 ± 3.3 years. In 12 neurologic Wilson disease cases, there were prolonged interpeak latencies of brainstem auditory evoked potentials III-V, I-V, somatosensory evoked potentials N13-N20 (P < 0.01 vs controls and non-neurologic cases), and P100 latency (P < 0.01 vs controls). All 12 patients had at least one abnormal evoked potential, including 91.7% brainstem auditory, 58.3% somatosensory, and 25% visual evoked potentials. In 18 non-neurologic Wilson disease cases, there were still prolonged interpeak latencies for brainstem auditory evoked potentials I-V and somatosensory evoked potentials N13-N20 (P < 0.05 vs controls), with 27.8% of them having at least one abnormal evoked potential, including 16.6% brainstem auditory, 5.6% somatosensory, and 11.1% visual evoked potentials. In those with non-neurologic Wilson disease, there were no significant differences in all the evoked potential parameters between the cirrhotic and non-cirrhotic patients. ? 2003 by Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141678296&doi=10.1016%2fS0887-8994%2803%2900026-2&partnerID=40&md5=c4b2a4b655f81eac3f905b8e60851c41 https://scholars.lib.ntu.edu.tw/handle/123456789/537128 |
ISSN: | 0887-8994 | DOI: | 10.1016/S0887-8994(03)00026-2 | SDG/關鍵字: | adolescent; adult; analytical parameters; article; clinical article; controlled study; diagnostic procedure; diagnostic value; disease duration; evoked brain stem auditory response; evoked somatosensory response; evoked visual response; female; human; latent period; liver cirrhosis; male; neurologic disease; pediatrics; priority journal; school child; Wilson disease |
顯示於: | 醫學系 |
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