|Title:||Amniocentesis in mothers who are hepatitis B virus carriers does not expose the infant to an increased risk of hepatitis B virus infection||Authors:||Ko T.-M.
|Issue Date:||1994||Publisher:||Springer-Verlag||Journal Volume:||255||Journal Issue:||1||Start page/Pages:||25-30||Source:||Archives of Gynecology and Obstetrics||Abstract:||
Sixty-seven pairs of mothers with hepatitis B virus (HBV) surface antigen (HBsAg) and their infants were divided into two study groups to determine the effect of amniocentesis on intrauterine HBV infection. In the first study group (35 pairs), the infant's HBsAg status in cord blood was studied and the results were compared with those obtained in the cord blood from 65 infants born to HBsAg-positive women who did not have an amniocentesis. In the second study group (32 pairs), the HBV status of the infants was studied at the age of three months to five years and compared with the HBV status of 3,454 infants in the National HBV Prevention Program. In the first study group, one sample (2.9%) was weakly positive for HBsAg; while in the first control group, two (3.1%) were positive. In the second study group, three (10%) infants were positive for HBsAg. The failure rates of immunoprophylaxis in the second study and control groups were similar (9.4% vs 11% for HBsAg carrier mothers; 30% vs 14% for HBe antigen-positive carrier mothers). This suggested that genetic amniocentesis did not increase the risk of intrauterine HBV infection. ? 1994 Springer-Verlag.
|ISSN:||0932-0067||DOI:||10.1007/BF02390671||SDG/Keyword:||hepatitis b antibody; hepatitis b surface antigen; hepatitis b(e) antigen; amniocentesis; article; clinical article; controlled study; follow up; hepatitis b; hepatitis b virus; human; immunoprophylaxis; infant; infection risk; intramuscular drug administration; intrauterine infection; mother; umbilical cord blood; Adult; Amniocentesis; Carrier State; Female; Fetal Blood; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Human; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Risk Factors
|Appears in Collections:||醫學系|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.