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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/537482
Title: Prognostic factors of treatment outcomes in patients with granulocytic sarcoma
Authors: Lan T.-Y.
Lin D.-T.
HWEI-FANG TIEN 
RONG-SEN YANG 
Chen C.-Y.
Wu K.
Issue Date: 2009
Journal Volume: 122
Journal Issue: 4
Start page/Pages: 238-246
Source: Acta Haematologica
Abstract: 
Purpose: To investigate the possible prognostic factors of survival outcomes in patients with granulocytic sarcoma (GS). Methods: We retrospectively investigated the prognostic factors determining survival in 24 patients with GS using Kaplan-Meier survival analysis followed by log rank tests. We evaluated gender, age, location, GS antedating leukemia, underlying disorders, treatment type and stem cell transplantation. Results: The 5-year survival rate for the patients with GS was 21%. The patients undergoing chemotherapy had a significantly longer survival time compared to those who did not (p = 0.0009). We found no difference in the 5-year survival rate among the patients undergoing chemotherapy combined with radiation or surgery. Patients with chronic myelogenous leukemia and myelodysplastic disorders had worse survival rates (p = 0.0028). Conclusion: Early diagnosis with biopsy and early chemotherapy can improve survival outcome. Local radiation or surgery can improve symptoms but does not influence survival outcomes. ? 2009 S. Karger AG, Basel.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350557176&doi=10.1159%2f000253592&partnerID=40&md5=f12981d42bbc01621c5f5b25b9ef4b81
https://scholars.lib.ntu.edu.tw/handle/123456789/537482
ISSN: 0001-5792
DOI: 10.1159/000253592
SDG/Keyword: cyclophosphamide; cytarabine; idarubicin; adolescent; adult; age distribution; aged; allogeneic hematopoietic stem cell transplantation; article; cancer chemotherapy; cancer diagnosis; cancer localization; cancer radiotherapy; cancer surgery; cancer survival; cause of death; child; chronic myeloid leukemia; clinical article; controlled study; cytogenetics; diagnostic imaging; female; follow up; granulocytic sarcoma; histopathology; human; male; medical record review; myelodysplastic syndrome; onset age; preschool child; priority journal; prognosis; school child; sex difference; stem cell transplantation; survival rate; treatment outcome; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Retrospective Studies; Sarcoma, Myeloid; Translocation, Genetic; Treatment Outcome; Young Adult
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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