An Asian patient with intraocular lymphoma treated by intravitreal methotrexate
Journal
Japanese Journal of Ophthalmology
Journal Volume
50
Journal Issue
5
Pages
474-478
Date Issued
2006
Author(s)
Abstract
Background: To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma. Case: A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma. Observations: The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up. Conclusion: Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma. ? Japanese Ophthalmological Society 2006.
Subjects
Chemotherapy; Intraocular lymphoma; Intravitreal injection; Methotrexate; Primary central nervous system lymphoma
SDGs
Other Subjects
methotrexate; adult; article; cancer chemotherapy; cancer regression; case report; cornea disease; cornea epitheliopathy; cornea epithelium; drug efficacy; drug megadose; drug safety; eye pain; follow up; human; immunocompetence; iritis; lymphoma; male; priority journal; vitreous body; vitreous disease; vitritis; Antimetabolites, Antineoplastic; Biopsy; Diagnosis, Differential; Eye Neoplasms; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Injections; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Taiwan; Vitreous Body
Type
journal article