https://scholars.lib.ntu.edu.tw/handle/123456789/537507
Title: | An Asian patient with intraocular lymphoma treated by intravitreal methotrexate | Authors: | JIA-KANG WANG CHUNG-MAY YANG CHANG-PING LIN Shan Y.-D. Lo A.Y. HWEI-FANG TIEN |
Keywords: | Chemotherapy; Intraocular lymphoma; Intravitreal injection; Methotrexate; Primary central nervous system lymphoma | Issue Date: | 2006 | Journal Volume: | 50 | Journal Issue: | 5 | Start page/Pages: | 474-478 | Source: | Japanese Journal of Ophthalmology | Abstract: | Background: To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma. Case: A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma. Observations: The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up. Conclusion: Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma. ? Japanese Ophthalmological Society 2006. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33749319975&doi=10.1007%2fs10384-005-0327-4&partnerID=40&md5=0e071edd1a3c884b53349475d9b9ac2d https://scholars.lib.ntu.edu.tw/handle/123456789/537507 |
ISSN: | 0021-5155 | DOI: | 10.1007/s10384-005-0327-4 | SDG/Keyword: | methotrexate; adult; article; cancer chemotherapy; cancer regression; case report; cornea disease; cornea epitheliopathy; cornea epithelium; drug efficacy; drug megadose; drug safety; eye pain; follow up; human; immunocompetence; iritis; lymphoma; male; priority journal; vitreous body; vitreous disease; vitritis; Antimetabolites, Antineoplastic; Biopsy; Diagnosis, Differential; Eye Neoplasms; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Injections; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Taiwan; Vitreous Body |
Appears in Collections: | 醫學系 |
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