https://scholars.lib.ntu.edu.tw/handle/123456789/537568
標題: | Primary T cell leptomeningeal lymphoma – Successful treatment with systemic chemotherapy | 作者: | KUN-HUEI YEH ANN-LII CHENG HWEI-FANG TIEN |
公開日期: | 1995 | 卷: | 52 | 期: | 6 | 起(迄)頁: | 501-504 | 來源出版物: | Oncology (Switzerland) | 摘要: | Primary central nervous system lymphoma (PCNSL) is rare, accounting for only 1–2% of non-Hodgkin’s lymphoma, and primary isolated leptomeningeal lymphoma is even rarer. It may create a diagnostic problem, particularly when the tumor cells are of T cell lineage. We herein report a patient with primary T cell leptomeningeal lymphoma. The final diagnosis was confirmed by the cytogenetic study which revealed clonal aberration, isochromosome of long arm of chromosome 7, in the lymphoid cells from CSF. She was treated with a novel protocol of systemic chemotherapy specifically designed for the CNS lymphoma. The regimen consisted of carmustine, vincristine, high-dose methotrexate, etoposide, and methylprednisolone. A total of 5 courses were given and she was still in complete remission at the time of reporting, 21 months after the establishment of diagnosis. ? 1995 S. Karger AG, Basel. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028799075&doi=10.1159%2f000227519&partnerID=40&md5=cef2ce94d853f07a92bf6fcca32ff8a8 https://scholars.lib.ntu.edu.tw/handle/123456789/537568 |
ISSN: | 0030-2414 | DOI: | 10.1159/000227519 | SDG/關鍵字: | carmustine; ethambutol; etoposide; glycerol; isoniazid; methotrexate; methylprednisolone; methylprednisolone sodium succinate; rifampicin; steroid; tuberculostatic agent; vincristine sulfate; adult; article; brain lymphoma; cancer chemotherapy; cancer diagnosis; cancer regression; case report; cerebrospinal fluid cytology; chromosome 7; chromosome aberration; cytogenetics; female; human; intravenous drug administration; leptomeninx; lymphoid cell; oral drug administration; priority journal; t cell lymphoma; treatment outcome; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Case Report; Etoposide; Female; Human; Lymphoma, T-Cell; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Methylprednisolone Hemisuccinate; Remission Induction; Vincristine |
顯示於: | 醫學系 |
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