https://scholars.lib.ntu.edu.tw/handle/123456789/538017
標題: | Successful treatment of acute hepatitis A-associated hemophagocytic syndrome by intravenous immunoglobulin | 作者: | Tai C.-M. CHUN-JEN LIU MING YAO |
公開日期: | 2005 | 卷: | 104 | 期: | 7 | 起(迄)頁: | 507-510 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Virus-associated hemophagocytic syndrome (VAHS) is a rare complication in acute hepatitis A virus (HAV) infection. There is no standard therapy for VAHS and the clinical course is variable. Data on the use of intravenous immunoglobulin (IVIG) in the treatment of HAV-associated VAHS is limited. We report a previously healthy, 32-year-old man who presented with general malaise, fever, chills and splenomegaly. Laboratory examination showed marked elevation of aminotransferase, leukopenia and thrombocytopenia. Acute hepatitis A was documented by the presence of immunoglobulin M anti-HAV and compatible liver biopsy findings. Bone marrow examination revealed extensive hemophagocytosis, IVIG was administered after the diagnosis of HAV-associated VAHS. His symptoms and laboratory abnormalities improved, and following a smooth recovery he was discharged 1 month after admission. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-24944491770&partnerID=40&md5=e0527e18f75e802d2d203874bedc12d5 https://scholars.lib.ntu.edu.tw/handle/123456789/538017 |
ISSN: | 0929-6646 | SDG/關鍵字: | aminotransferase; hepatitis A antibody; immunoglobulin M; immunoglobulin; acute hepatitis; adult; aminotransferase blood level; article; bone marrow examination; case report; chill; clinical feature; convalescence; disease association; erythrophagocytosis; fever; hemophagocytic syndrome; hepatitis A; human; human tissue; laboratory test; leukopenia; liver biopsy; malaise; male; splenomegaly; thrombocytopenia; treatment outcome; acute disease; hepatitis A; histiocytosis; Acute Disease; Adult; Hepatitis A; Histiocytosis, Non-Langerhans-Cell; Humans; Immunoglobulins, Intravenous; Male |
顯示於: | 醫學系 |
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