https://scholars.lib.ntu.edu.tw/handle/123456789/538190
標題: | Quality of life after adenotonsillectomy for children with sleep-disordered breathing: A linear mixed model analysis | 作者: | Lee, Chia-Hsuan Kang, Kun-Tai WEN-CHIN WENG PEI-LIN LEE WEI-CHUNG HSU |
公開日期: | 2014 | 出版社: | Elsevier Ireland Ltd | 卷: | 78 | 期: | 8 | 起(迄)頁: | 1374-1380 | 來源出版物: | International Journal of Pediatric Otorhinolaryngology | 摘要: | Objective: To study changes in quality of life (QoL) after adenotonsillectomy (T&A) in children with sleep-disordered breathing (SDB), and to elucidate discrepancies in QoL improvements after T&A in children of different gender, age, adiposity status, and disease severity. Materials and methods: Children aged 2-18 years were recruited. All children had SDB-related symptoms and underwent preoperative full-night polysomnography (PSG). Caregivers completed the first obstructive sleep apnea 18-items questionnaire (OSA-18) prior to T&A and the second OSA-18 survey within 3 months after surgery. Disease severity was defined as primary snoring (apnea/hypopnea index, AHI < 1), mild obstructive sleep apnea (OSA) (5 > AHI. ?1), and moderate-to-severe OSA (AHI ? 5). Discrepancies in OSA-18 score changes after T&A for different groups were assessed using the linear mixed model. Results: In total, 144 children were enrolled (mean age, 7.0 ± 3.6 years; 76% boy). The OSA-18 total score changes after surgery were not significantly different by gender (boys vs. girls), age group (?6 years vs. <6 years), or adiposity (obese vs. non-obese). The OSA-18 total score changes after surgery differed by disease severity (primary snoring vs. moderate-to-severe OSA, P= 0.004; mild OSA vs. moderate-to-severe OSA, P= 0.003). Children with moderate-to-severe OSA had greater improvement in OSA-18 total score after surgery than those with mild OSA or primary snoring. Conclusions: Children with SDB had QoL improvement after T&A, as documented by OSA-18 score changes. The QoL improvement after T&A for SDB children increased as disease severity increased, and the improvement was not affected by gender, age, or adiposity. ? 2014 Elsevier Ireland Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904067541&doi=10.1016%2fj.ijporl.2014.05.038&partnerID=40&md5=6288c50242710ecc63d3c970374adf87 https://scholars.lib.ntu.edu.tw/handle/123456789/538190 |
ISSN: | 0165-5876 | DOI: | 10.1016/j.ijporl.2014.05.038 | SDG/關鍵字: | adenotonsillectomy; adolescent; adult; article; child; controlled study; disease severity; female; groups by age; human; linear mixed model analysis; major clinical study; male; obesity; obstructive sleep apnea 18; polysomnography; preoperative period; priority journal; quality of life; questionnaire; scoring system; sex difference; sleep disordered breathing; statistical analysis; adenoidectomy; preschool child; severity of illness index; Sleep Apnea Syndromes; statistical model; tonsillectomy; Adenoidectomy; Adolescent; Child; Child, Preschool; Female; Humans; Linear Models; Male; Quality of Life; Questionnaires; Severity of Illness Index; Sleep Apnea Syndromes; Tonsillectomy |
顯示於: | 醫學系 |
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