Postnatal cumulative incidence of supraventricular tachycardia in a general pediatric population: A national birth cohort database study
Journal
Heart Rhythm
Journal Volume
13
Journal Issue
10
Pages
2070-2075
Date Issued
2016
Author(s)
Abstract
Background Supraventricular tachycardia (SVT) is a common pediatric tachycardia, but the true incidence is unknown. Objective We sought to investigate the true postnatal incidence and its medical needs. Methods We derived a birth cohort comprised children born between 2000 and 2008 who had complete postnatal medical data in the Taiwan National Health Insurance Database for the period from 2000 to 2014. Results From 1,967,911 live births, we identified 2021 patients with SVT (51.6% men), accounting for an overall incidence of 1.03 per 1000 patient-years (Wolff-Parkinson-White syndrome accounted for 16.2%). The cumulative incidence was 0.06, 0.25, 0.45, 0.88, and 1.39 per 1000 patient-years by the age of 1 month, 1 year, 5 years, 10 years, and 15 years, respectively. Major congenital heart disease (5.3%; hazard ratio 6.66; 95% confidence interval 2.98–14.87) and cardiomyopathy (0.9%; hazard ratio 8.78; 95% confidence interval 3.39–22.78) were associated with mortality. In patients without major congenital heart disease, the cumulative incidence of SVT was 0.05, 0.22, 0.41, 0.84, and 1.33 per 1000 patient-years by the age of 1 month, 1 year, 5 years, 10 years, and 15 years, respectively. By the age of 15 years, the annual risk of death and sudden death was 0.13% and 0.01% per patient-year, respectively. Radiofrequency catheter ablation was performed in 173 patients at the median age of 11 years: 1.7% during infancy, 5.8% by the age of 5 years, and 31.8% by the age of 10 years. The probability of being free from receiving ablation by the age of 15 years was 83.4%. Conclusion This birth cohort study provides the true incidence of pediatric SVT and indicates that almost one-fifth of the patients with SVT have already received ablation in the pediatric ages. ? 2016 Heart Rhythm Society
Subjects
Birth cohort; Cumulative incidence; Incidence; Radiofrequency catheter ablation; Supraventricular tachycardia; Wolff-Parkinson-White syndrome
SDGs
Other Subjects
adolescent; Article; cardiomyopathy; cardiovascular mortality; child; childhood disease; cohort analysis; data base; Ebstein anomaly; Fallot tetralogy; female; heart atrium septum defect; heart rhythm; heart ventricle septum defect; human; infant; major clinical study; male; patent ductus arteriosus; perinatal period; pulmonary valve stenosis; radiofrequency catheter ablation; retrospective study; sudden death; supraventricular tachycardia; Taiwan; Wolff Parkinson White syndrome; cardiomyopathy; catheter ablation; complication; congenital heart malformation; incidence; needs assessment; newborn; outcome assessment; preschool child; procedures; prognosis; recurrent disease; supraventricular tachycardia; treatment outcome; Adolescent; Cardiomyopathies; Catheter Ablation; Child; Child, Preschool; Cohort Studies; Female; Heart Defects, Congenital; Humans; Incidence; Infant; Infant, Newborn; Male; Needs Assessment; Outcome Assessment (Health Care); Prognosis; Recurrence; Tachycardia, Supraventricular; Taiwan; Treatment Outcome
Publisher
Elsevier B.V.
Type
journal article