https://scholars.lib.ntu.edu.tw/handle/123456789/539540
標題: | A retrospective study on the usage of cough and cold medications in viral respiratory tract infections in Taiwanese children | 作者: | Cheng C.-L. Kao Yang Y.-H. Liu C.-C. PING-ING LEE |
關鍵字: | Children; Cold; Medications; National Health Insurance Research Database; Pharmacoepidemiology; Taiwan; Viral respiratory infections | 公開日期: | 2014 | 卷: | 23 | 期: | 1 | 起(迄)頁: | 36-42 | 來源出版物: | Pharmacoepidemiology and Drug Safety | 摘要: | Objective: We sought to describe the epidemiology of viral respiratory-tract infections and patterns in prescriptions of cough and cold medications among young children who were suffering from viral respiratory tract infections (vRTIs). Methods: We conducted a cross-sectional study to examine vRTI-episode occurrence and cold-medication utilization in outpatients in 2007 using the National Health Insurance Research Database (NHIRD) in Taiwan. One-third of the children under 12years of age who had at least one outpatient visit for a vRTI as randomly selected from NHIRD were included in the analysis. Results: A total of 895942 children had a diagnosis of vRTI (6144336 visits) during 2007, 58% of whom were aged 6 to 12years, and 52% of whom were male. The mean cumulative incidence of vRTIs by ages were 5.6 in infancy, 7.1 in preschool, and 4.0 in school children. The average number of cough and cold medications without other drugs prescribed per visit was two to three. Among cough and cold medications, antihistamines for systemic use were prescribed most frequently (20%), followed by mucolytics (12%), selective beta-2 agonists (11%), decongestants for systemic use (10%), and analgesic-antipyretics including acetaminophen (7%) or non-steroid anti-inflammatory drugs (6%). There was considerable variation of prescriptions, which increased with increasing age, where the top 20 prescription accounted for only 36%, 30%, and 25% of all prescriptions in infants, preschool, and school age children, respectively. Conclusions: A more rational use of medicines for treatment of vRTIs in children in Taiwan needs to be developed. ? 2013 John Wiley & Sons, Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891626116&doi=10.1002%2fpds.3460&partnerID=40&md5=7af9b2a807c5de443d1a388f381c1f6d https://scholars.lib.ntu.edu.tw/handle/123456789/539540 |
ISSN: | 1053-8569 | DOI: | 10.1002/pds.3460 | SDG/關鍵字: | antihistaminic agent; antiinfective agent; antitussive agent; beta 2 adrenergic receptor stimulating agent; decongestive agent; expectorant agent; mucolytic agent; nonsteroid antiinflammatory agent; opiate; paracetamol; xanthine derivative; article; child; common cold; coughing; cross-sectional study; drug utilization; female; human; incidence; infant; major clinical study; male; outpatient; preschool child; prescription; priority journal; retrospective study; school child; Taiwan; viral respiratory tract infection; children; cold; medications; National Health Insurance Research Database; pharmacoepidemiology; Taiwan; viral respiratory infections; Antitussive Agents; Child; Cross-Sectional Studies; Female; Humans; Male; Multi-Ingredient Cold, Flu, and Allergy Medications; Respiratory Tract Infections; Retrospective Studies; Taiwan; Virus Diseases |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。