https://scholars.lib.ntu.edu.tw/handle/123456789/540179
標題: | Functional assessment of expiratory flow pattern in feline lower airway disease | 作者: | Chung-Hui Lin Jih-Jong Lee CHEN-HSUAN LIU JIH-JONG LEE CHUNG-HUI LIN |
公開日期: | 2014 | 卷: | 16 | 期: | 8 | 起(迄)頁: | 616-622 | 來源出版物: | Journal of Feline Medicine and Surgery | 摘要: | Feline lower airway disease (FLAD) is a chronic respiratory disease of which there is a lack of information on functional assessment in current veterinary medicine. The purposes of this study were to investigate expiratory pattern and evaluate the diagnostic utility of functional parameters in cats with FLAD. Thirty-three client-owned cats (23 FLAD cats and 10 control cats) were studied. Under quiet tidal breathing, pseudo-tidal breathing flow-volume loop (pTBFVL) was obtained from a barometric whole body plethysmography (BWBP) device. There were significant differences in the shapes of expiratory, but not inspiratory, curves between FLAD and control cats. The incidence of the presence of concave expiratory curve indicating lower airway obstruction was 74% in FLAD cats. To assess the diagnostic utility of pTBFVL indices in cats with FLAD, area under the receiver-operator curve was 0.86 for PEF/EF50 (peak expiratory flow divided by expiratory flow at end expiratory volume plus 50% tidal volume); a cuff-off value of PEF/EF50 >1.51 distinguished normal from FLAD (73.9% sensitivity, 100% specificity). There were no significant differences in traditionally measured BWBP parameters (ie, enhanced pause) between cats with and without FLAD in the present study. In conclusion, underlying change on expiratory flow pattern during natural tidal breathing existed in FLAD cats, and selected pTBFVL indices were useful in discriminating FLAD from normal cats. Tidal breathing pattern depicted by pseudoflow-pseudovolume loops from a BWBP system could be a non-invasive tool for functional assessment in client-owned cats. ? ISFM and AAFP 2013. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/540179 | DOI: | 10.1177/1098612X13515461 | SDG/關鍵字: | animal; cat; Cat Diseases; comparative study; lung ventilation; lung volume; reference value; respiratory tract disease; tidal volume; veterinary; Animals; Cat Diseases; Cats; Lung Volume Measurements; Pulmonary Ventilation; Reference Values; Respiratory Tract Diseases; Tidal Volume |
顯示於: | 臨床動物醫學研究所 |
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