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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/540476
Title: Clinical profiles of multiple myeloma in Asia-An Asian Myeloma Network study
Authors: Kim K.
Lee J.H.
Kim J.S.
Min C.K.
Yoon S.S.
Shimizu K.
Chou T.
Kosugi H.
Suzuki K.
Chen W.
Hou J.
Lu J.
Huang X.-J.
SHANG-YI HUANG 
Chng W.J.
Tan D.
Teoh G.
Chim C.S.
Nawarawong W.
Siritanaratkul N.
Durie B.G.
Issue Date: 2014
Publisher: Wiley-Liss Inc.
Journal Volume: 89
Journal Issue: 7
Start page/Pages: 751-756
Source: American Journal of Hematology
Abstract: 
The incidence of multiple myeloma (MM) is known to be variable according to ethnicity. However, the differences in clinical characteristics between ethnic groups are not well-defined. In Asian countries, although the incidence of MM has been lower than that of Western countries, there is growing evidence that MM is increasing rapidly. The Asian Myeloma Network decided to initiate the first multinational project to describe the clinical characteristics of MM and the clinical practices in Asia. Data were retrospectively collected from 23 centers in 7 countries and regions. The clinical characteristics at diagnosis, survival rates and initial treatment of 3,405 symptomatic MM patients were described. Median age was 62 years (range, 19-106), with 55.6% of being male. Median overall survival (OS) was 47 months (95% CI 44.0-50.0). Stem cell transplantation was performed in 666 patients who showed better survival rates (79 vs. 41 months, P<0.001). The first-line treatments of 2,970 patients were analyzed. The overall response rate was 71% including very good partial response or better in 31% of the 2,660 patients those were able to be evaluated. New drugs including bortezomib, thalidomide, and lenalidomide were used in 36% of 2,970 patients and affected OS when used as a first-line treatment. Am. J. Hematol. 89:751-756, 2014. ? 2014 Wiley Periodicals, Inc.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902775045&doi=10.1002%2fajh.23731&partnerID=40&md5=7bd5ee271d0c66ea1bf37ef2b3df9bcf
https://scholars.lib.ntu.edu.tw/handle/123456789/540476
ISSN: 0361-8609
DOI: 10.1002/ajh.23731
metadata.dc.subject.other: beta 2 microglobulin; bortezomib; calcium; creatinine; hemoglobin; immunoglobulin A; immunoglobulin D; immunoglobulin G; immunoglobulin heavy chain; lenalidomide; serum albumin; thalidomide; adult; age distribution; aged; article; Asia; Asian; autologous stem cell transplantation; bone lesion; bone marrow cell; calcium blood level; cancer survival; China; clinical feature; clinical practice; creatinine blood level; diploidy; female; genetic polymorphism; hemoglobin blood level; Hong Kong; human; Japan; Korea; major clinical study; male; multicenter study; multiple myeloma; overall survival; plasma cell; plasmacytoma; priority journal; retrospective study; Singapore; survival rate; Taiwan; Thailand; thrombocyte count; treatment response; very elderly; Adult; Aged; Aged, 80 and over; Asia; Female; Humans; Incidence; Male; Middle Aged; Multiple Myeloma; Prognosis; Retrospective Studies; Survival Analysis; Young Adult
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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