Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Comparison of a Chinese herbal medicine (CCH1) and lactulose as first-line treatment of constipation in long-term care: A randomized, double-blind, double-dummy, and placebo-controlled trial
 
  • Details

Comparison of a Chinese herbal medicine (CCH1) and lactulose as first-line treatment of constipation in long-term care: A randomized, double-blind, double-dummy, and placebo-controlled trial

Journal
Evidence-based Complementary and Alternative Medicine
Journal Volume
2012
Date Issued
2012
Author(s)
Huang C.-H.
Lin J.-S.
Li T.-C.
Lee S.-C.
HSIU-PO WANG  
Lue H.-C.
Su Y.-C.
DOI
10.1155/2012/923190
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859735962&doi=10.1155%2f2012%2f923190&partnerID=40&md5=f435a7f2782934b286472467de4a2d6d
https://scholars.lib.ntu.edu.tw/handle/123456789/541023
Abstract
Many institutionalized patients and their healthcare providers are dissatisfied with current laxative therapy. This study compared therapeutic efficacy, safety, and laxative cost of an herbal formula (CCH1) and lactulose for long stay patients with constipation. In this double-blind, double-dummy, and placebo-controlled trial, we randomized 93 residents with chronic constipation from two long-term care facilities in Taiwan to receive either CCH1 with lactulose placebo or CCH1 placebo with lactulose for 8 weeks, then followed up for 4 weeks without study medication. Both treatments were effective and well tolerated for patients, but CCH1 produced more spontaneous bowel movements, less rectal treatments, less amount of rescue laxative, and lower laxative cost than lactulose during treatment. No significant differences were found in stool consistency, stool amount, global assessment, and safety concerns. In conclusion, our results suggest that CCH1 may have better efficacy and could be used as an alternative option to lactulose in the treatment of constipation in long-term care. Copyright ? 2012 Chien-Hsun Huang et al.
SDGs

[SDGs]SDG3

Other Subjects
Aconitum carmichaeli extract; Atractylodes macrocephala extract; ginger extract; ginseng extract; Glycyrrhiza uralensis extract; herbaceous agent; lactulose; magnesium oxide; placebo; Rheum tanguticum extract; unclassified drug; abdominal pain; acute gastroenteritis; adult; aged; article; bloating; cellulitis; chest tightness; constipation; controlled study; coughing; creatine kinase blood level; diaper dermatitis; diarrhea; dizziness; double blind procedure; drug cost; drug dose titration; drug efficacy; drug eruption; drug safety; drug tolerability; erythrocyte; feces analysis; female; flatulence; gastroesophageal reflux; hiccup; human; ileus; intestine motility; leukocyte; major clinical study; male; medicinal plant; nausea; parallel design; pneumonia; priority journal; pruritus; randomized controlled trial; side effect; Taiwan; thrombocyte; upper gastrointestinal bleeding; urea nitrogen blood level; urinary tract infection; vomiting
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science