https://scholars.lib.ntu.edu.tw/handle/123456789/542000
標題: | Initial 10-year experience of sperm cryopreservation services for cancer patients | 作者: | HONG-CHIANG CHANG Chen S.-C. Chen J. JU-TON HSIEH |
關鍵字: | Cancer; Chemotherapy; Cryopreservation; Male infertility; Sperm | 公開日期: | 2006 | 出版社: | Scientific Communications International Ltd | 卷: | 105 | 期: | 12 | 起(迄)頁: | 1022-1026 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Offering sperm cryopreservation to preserve the fertility of male cancer patients is a relatively recent service in Asia. This study analyzed the types of cancer, timing of collection, sperm quality, and utilization for reproductive services by patients during a 10-year period at a medical center in Taiwan. A total of 75 oncology patients elected to freeze sperm for fertility preservation at our medical center during the initial 10 years of the availability of this service. The mean age of the patients was 25.7 years. Storage was discontinued in 13 (17%) patients and their survival duration was 13.1 ± 11.1 months. The utilization rate of sperm cryopreservation was 2.8% (75/2642). The types of cancer varied, with leukemia (35%), lymphoma (25%), and testicular cancer (13%) comprising the largest groups. A significantly lower sperm count was found in patients with chronic myelogenous leukemia, suggesting the need for earlier sperm collection after initiation of cancer treatment. Only three (4%) patients utilized their specimens for reproductive purposes. There was no clinical pregnancy during the study period, although one biochemical pregnancy was achieved. The low rates of sperm cryostorage for fertility preservation in cancer patients in this study suggest that there is a need for greater emphasis of this option for male oncology patients whose fertility is likely to be affected by chemotherapeutic treatment. ? 2006 Elsevier & Formosan Medical Association. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846269298&doi=10.1016%2fS0929-6646%2809%2960288-6&partnerID=40&md5=4913c6a55d768b0524de5eafbdc37694 https://scholars.lib.ntu.edu.tw/handle/123456789/542000 |
ISSN: | 0929-6646 | DOI: | 10.1016/S0929-6646(09)60288-6 | SDG/關鍵字: | acute granulocytic leukemia; acute lymphoblastic leukemia; adolescent; adult; article; asthenospermia; cancer patient; chronic myeloid leukemia; cryopreservation; health service; human; lymphoma; major clinical study; male; male infertility; oligospermia; reproduction; sperm preservation; spermatozoon count; spermatozoon motility; survival time; Taiwan; testis cancer |
顯示於: | 醫學系 |
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